Drug interactions
Metaproterenol + Salbutamol
Severity: Moderate
Metaproterenol and Salbutamol: moderate interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Metaproterenol is another beta-agonist bronchodilator, so combining it with salbutamol duplicates therapy. This increases the risk of tachycardia, tremor, arrhythmias and hypokalemia without added benefit.
What this interaction means in plain words
Metaproterenol and Salbutamol can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Why it happens
Additive beta-adrenergic agonism from two drugs of the same class.
What to do
Avoid concurrent use and choose one short-acting beta-agonist. If both were used, monitor heart rate and serum potassium.
What to ask your pharmacist
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
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Other interactions of Salbutamol
Frequently asked questions
Can I take Metaproterenol with Salbutamol?
MediHelp rates the interaction as moderate. Metaproterenol and Salbutamol can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Metaproterenol is another beta-agonist bronchodilator, so combining it with salbutamol duplicates therapy. This increases the risk of tachycardia, tremor, arrhythmias and hypokalemia without added benefit.
How serious is the interaction between Metaproterenol and Salbutamol?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Avoid concurrent use and choose one short-acting beta-agonist. If both were used, monitor heart rate and serum potassium.
What other medicines interact with Salbutamol?
MediHelp also lists interactions of Salbutamol with, for example, Arsenic trioxide, Carvedilol, Droperidol. The full list is on the Salbutamol page.
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