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Drug interactions

Metformin-sitagliptin + Oxymetholone

Severity: Minor

Metformin-sitagliptin and Oxymetholone: minor interaction.

Last updated

For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.

Summary

Oxymetholone, an anabolic steroid, may lower blood glucose and enhance the response to antidiabetic drugs. The effect is variable and typically small with metformin and sitagliptin.

What this interaction means in plain words

Metformin-sitagliptin and Oxymetholone have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.

Evidence level: Low

Why it happens

Anabolic androgens may increase insulin sensitivity, giving a possible additive glucose-lowering effect.

What to do

Monitor blood glucose during oxymetholone therapy and reduce antidiabetic doses only if glucose falls.

What to ask your pharmacist

  • Is there anything I should notice while taking both?
  • Do I need to tell my doctor at the next visit?

Bring a full list of your medicines, including over-the-counter products, supplements and herbal remedies, to every pharmacy visit.

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Frequently asked questions

Can I take Metformin-sitagliptin with Oxymetholone?

MediHelp rates the interaction as minor. Metformin-sitagliptin and Oxymetholone have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Oxymetholone, an anabolic steroid, may lower blood glucose and enhance the response to antidiabetic drugs. The effect is variable and typically small with metformin and sitagliptin.

How serious is the interaction between Metformin-sitagliptin and Oxymetholone?

MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor blood glucose during oxymetholone therapy and reduce antidiabetic doses only if glucose falls.

What other medicines interact with Metformin-sitagliptin?

MediHelp also lists interactions of Metformin-sitagliptin with, for example, Clozapine, Contrast media, Diatrizoate meglumine / diatrizoate. The full list is on the Metformin-sitagliptin page.

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