Drug interactions
Octreotide + Olodaterol inhaled
Severity: Moderate
Octreotide and Olodaterol inhaled: moderate interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Olodaterol, a long-acting beta2 agonist, may prolong the QT interval and cause hypokalemia and tachycardia. Octreotide can add QT effects and bradycardia, so arrhythmia risk may be raised in patients with cardiac disease.
What this interaction means in plain words
Octreotide and Olodaterol inhaled can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Why it happens
Additive QT prolongation with beta2-agonist-induced hypokalemia and sympathetic stimulation.
What to do
Monitor ECG and serum potassium in patients with cardiac risk factors. Do not exceed the recommended olodaterol dose.
What to ask your pharmacist
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
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Other interactions of Octreotide
Frequently asked questions
Can I take Octreotide with Olodaterol inhaled?
MediHelp rates the interaction as moderate. Octreotide and Olodaterol inhaled can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Olodaterol, a long-acting beta2 agonist, may prolong the QT interval and cause hypokalemia and tachycardia. Octreotide can add QT effects and bradycardia, so arrhythmia risk may be raised in patients with cardiac disease.
How serious is the interaction between Octreotide and Olodaterol inhaled?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor ECG and serum potassium in patients with cardiac risk factors. Do not exceed the recommended olodaterol dose.
What other medicines interact with Octreotide?
MediHelp also lists interactions of Octreotide with, for example, Adagrasib, Amisulpride, Arsenic trioxide. The full list is on the Octreotide page.
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