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Drug interactions

Octreotide + Umeclidinium bromide / vilanterol inhaled

Severity: Minor

Octreotide and Umeclidinium bromide / vilanterol inhaled: minor interaction.

Last updated

For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.

Summary

Vilanterol, a long-acting beta agonist, can prolong QTc and raise heart rate. Octreotide may add conduction effects, though inhaled systemic exposure is low at usual doses.

What this interaction means in plain words

Octreotide and Umeclidinium bromide / vilanterol inhaled have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.

Evidence level: Low

Why it happens

Possible additive QT effects; vilanterol beta-agonist cardiac stimulation with octreotide-related conduction changes.

What to do

No routine change is needed. Monitor heart rate and ECG in patients with existing QT risk factors or cardiac disease.

What to ask your pharmacist

  • Is there anything I should notice while taking both?
  • Do I need to tell my doctor at the next visit?

Bring a full list of your medicines, including over-the-counter products, supplements and herbal remedies, to every pharmacy visit.

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Frequently asked questions

Can I take Octreotide with Umeclidinium bromide / vilanterol inhaled?

MediHelp rates the interaction as minor. Octreotide and Umeclidinium bromide / vilanterol inhaled have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Vilanterol, a long-acting beta agonist, can prolong QTc and raise heart rate. Octreotide may add conduction effects, though inhaled systemic exposure is low at usual doses.

How serious is the interaction between Octreotide and Umeclidinium bromide / vilanterol inhaled?

MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: No routine change is needed. Monitor heart rate and ECG in patients with existing QT risk factors or cardiac disease.

What other medicines interact with Octreotide?

MediHelp also lists interactions of Octreotide with, for example, Adagrasib, Amisulpride, Arsenic trioxide. The full list is on the Octreotide page.

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