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Drug interactions

Octreotide + Vilanterol / fluticasone furoate inhaled

Severity: Minor

Octreotide and Vilanterol / fluticasone furoate inhaled: minor interaction.

Last updated

For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.

Summary

Vilanterol can raise heart rate and prolong QTc, and octreotide may add conduction effects. Systemic exposure from inhaled vilanterol is low, so the clinical effect is usually small.

What this interaction means in plain words

Octreotide and Vilanterol / fluticasone furoate inhaled have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.

Evidence level: Low

Why it happens

Possible additive QT effects from beta-agonist stimulation and octreotide-related conduction changes.

What to do

No routine change is needed. Monitor ECG and heart rate in patients with cardiac disease or other QT risk factors.

What to ask your pharmacist

  • Is there anything I should notice while taking both?
  • Do I need to tell my doctor at the next visit?

Bring a full list of your medicines, including over-the-counter products, supplements and herbal remedies, to every pharmacy visit.

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Frequently asked questions

Can I take Octreotide with Vilanterol / fluticasone furoate inhaled?

MediHelp rates the interaction as minor. Octreotide and Vilanterol / fluticasone furoate inhaled have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Vilanterol can raise heart rate and prolong QTc, and octreotide may add conduction effects. Systemic exposure from inhaled vilanterol is low, so the clinical effect is usually small.

How serious is the interaction between Octreotide and Vilanterol / fluticasone furoate inhaled?

MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: No routine change is needed. Monitor ECG and heart rate in patients with cardiac disease or other QT risk factors.

What other medicines interact with Octreotide?

MediHelp also lists interactions of Octreotide with, for example, Adagrasib, Amisulpride, Arsenic trioxide. The full list is on the Octreotide page.

Full monographs, dosing and an interaction checker in the MediHelp app

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