Drug interactions
Albuterol + Ofloxacin
Severity: Moderate
Albuterol and Ofloxacin: moderate interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Albuterol can cause tachycardia, hypokalemia and QT effects, and ofloxacin has a small QT-prolonging potential. Together they may modestly increase arrhythmia risk, mainly with high-dose or nebulized albuterol or in patients with heart disease.
What this interaction means in plain words
Albuterol and Ofloxacin can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Why it happens
Additive effects on cardiac repolarization with beta2-agonist-induced hypokalemia and tachycardia.
What to do
Monitor potassium in patients using frequent or high-dose albuterol. Consider an ECG in patients with known QT prolongation or cardiac disease.
What to ask your pharmacist
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
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Other interactions of Ofloxacin
- Ofloxacin + Thioridazine Contraindicated
- Adagrasib + Ofloxacin Major
- Amiodarone + Ofloxacin Major
- Amisulpride + Ofloxacin Major
- Anagrelide + Ofloxacin Major
- Arsenic trioxide + Ofloxacin Major
Frequently asked questions
Can I take Albuterol with Ofloxacin?
MediHelp rates the interaction as moderate. Albuterol and Ofloxacin can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Albuterol can cause tachycardia, hypokalemia and QT effects, and ofloxacin has a small QT-prolonging potential. Together they may modestly increase arrhythmia risk, mainly with high-dose or nebulized albuterol or in patients with heart disease.
How serious is the interaction between Albuterol and Ofloxacin?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor potassium in patients using frequent or high-dose albuterol. Consider an ECG in patients with known QT prolongation or cardiac disease.
What other medicines interact with Ofloxacin?
MediHelp also lists interactions of Ofloxacin with, for example, Thioridazine, Adagrasib, Amiodarone. The full list is on the Ofloxacin page.
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