Drug interactions
Olanzapine + Sage
Severity: Minor
Olanzapine and Sage: minor interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Some sage species have reported sedative properties that could theoretically add to olanzapine drowsiness. Clinical evidence of a meaningful interaction is lacking.
What this interaction means in plain words
Olanzapine and Sage have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Why it happens
Possible additive CNS depression; the mechanism is not well established.
What to do
No routine change is needed. Advise patients to report excess sedation if they use sage supplements.
What to ask your pharmacist
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
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Other interactions of Olanzapine
Frequently asked questions
Can I take Olanzapine with Sage?
MediHelp rates the interaction as minor. Olanzapine and Sage have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Some sage species have reported sedative properties that could theoretically add to olanzapine drowsiness. Clinical evidence of a meaningful interaction is lacking.
How serious is the interaction between Olanzapine and Sage?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: No routine change is needed. Advise patients to report excess sedation if they use sage supplements.
What other medicines interact with Olanzapine?
MediHelp also lists interactions of Olanzapine with, for example, Amisulpride, Amoxapine, Apomorphine. The full list is on the Olanzapine page.
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