Drug interactions
Olodaterol inhaled + Pimozide
Severity: Moderate
Olodaterol inhaled and Pimozide: moderate interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Pimozide prolongs the QT interval and beta2 agonists can add cardiovascular effects, including tachycardia and hypokalemia. Together they may raise the risk of ventricular arrhythmias, although systemic exposure to inhaled olodaterol is low.
What this interaction means in plain words
Olodaterol inhaled and Pimozide can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Why it happens
Additive QT prolongation and beta2-mediated hypokalemia and tachycardia.
What to do
Check ECG and potassium in patients with additional cardiac risk factors. Use olodaterol only at the labeled dose.
What to ask your pharmacist
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
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Other interactions of Pimozide
- Adagrasib + Pimozide Contraindicated
- Amiodarone + Pimozide Contraindicated
- Amisulpride + Pimozide Contraindicated
- Amitriptyline + Pimozide Contraindicated
- Amoxapine + Pimozide Contraindicated
- Anagrelide + Pimozide Contraindicated
Frequently asked questions
Can I take Olodaterol inhaled with Pimozide?
MediHelp rates the interaction as moderate. Olodaterol inhaled and Pimozide can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Pimozide prolongs the QT interval and beta2 agonists can add cardiovascular effects, including tachycardia and hypokalemia. Together they may raise the risk of ventricular arrhythmias, although systemic exposure to inhaled olodaterol is low.
How serious is the interaction between Olodaterol inhaled and Pimozide?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Check ECG and potassium in patients with additional cardiac risk factors. Use olodaterol only at the labeled dose.
What other medicines interact with Pimozide?
MediHelp also lists interactions of Pimozide with, for example, Adagrasib, Amiodarone, Amisulpride. The full list is on the Pimozide page.
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