Drug interactions
Olodaterol inhaled + Terbutaline
Severity: Moderate
Olodaterol inhaled and Terbutaline: moderate interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Olodaterol is a long-acting beta-2 agonist, and adding terbutaline duplicates beta-2 stimulation. This may cause excessive tachycardia, tremor, palpitations, hypokalemia and arrhythmias, especially in patients with cardiovascular disease.
What this interaction means in plain words
Olodaterol inhaled and Terbutaline can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Why it happens
Additive beta-2 adrenergic receptor agonism.
What to do
Avoid regular use of another beta-2 agonist alongside olodaterol; reserve a short-acting agent for rescue use only. Monitor heart rate, tremor and serum potassium if used together.
What to ask your pharmacist
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
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Other interactions of Terbutaline
Frequently asked questions
Can I take Olodaterol inhaled with Terbutaline?
MediHelp rates the interaction as moderate. Olodaterol inhaled and Terbutaline can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Olodaterol is a long-acting beta-2 agonist, and adding terbutaline duplicates beta-2 stimulation. This may cause excessive tachycardia, tremor, palpitations, hypokalemia and arrhythmias, especially in patients with cardiovascular disease.
How serious is the interaction between Olodaterol inhaled and Terbutaline?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Avoid regular use of another beta-2 agonist alongside olodaterol; reserve a short-acting agent for rescue use only. Monitor heart rate, tremor and serum potassium if used together.
What other medicines interact with Terbutaline?
MediHelp also lists interactions of Terbutaline with, for example, Carvedilol, Droperidol, Fexinidazole. The full list is on the Terbutaline page.
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