Drug interactions
Olodaterol inhaled + Theophylline
Severity: Moderate
Olodaterol inhaled and Theophylline: moderate interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Theophylline and beta-2 agonists can each lower serum potassium, so combined use may produce additive hypokalemia. This raises the risk of arrhythmias, especially in hypoxic patients.
What this interaction means in plain words
Olodaterol inhaled and Theophylline can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Why it happens
Additive shift of potassium into cells through beta-2 stimulation and xanthine effects.
What to do
Monitor serum potassium in patients with risk factors such as acute exacerbations or diuretic use, and replace potassium as needed.
What to ask your pharmacist
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
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Other interactions of Theophylline
- Riociguat + Theophylline Contraindicated
- Adenosine + Theophylline Major
- Apalutamide + Theophylline Major
- Bupropion + Theophylline Major
- Carvedilol + Theophylline Major
- Cimetidine + Theophylline Major
Frequently asked questions
Can I take Olodaterol inhaled with Theophylline?
MediHelp rates the interaction as moderate. Olodaterol inhaled and Theophylline can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Theophylline and beta-2 agonists can each lower serum potassium, so combined use may produce additive hypokalemia. This raises the risk of arrhythmias, especially in hypoxic patients.
How serious is the interaction between Olodaterol inhaled and Theophylline?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor serum potassium in patients with risk factors such as acute exacerbations or diuretic use, and replace potassium as needed.
What other medicines interact with Theophylline?
MediHelp also lists interactions of Theophylline with, for example, Riociguat, Adenosine, Apalutamide. The full list is on the Theophylline page.
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