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Drug interactions

Albuterol + Pazopanib

Severity: Moderate

Albuterol and Pazopanib: moderate interaction.

Last updated

For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.

Summary

Pazopanib can prolong the QT interval, and albuterol, particularly at high or systemic doses, may add to this through beta-agonist effects and hypokalemia. Together they may modestly raise arrhythmia risk.

What this interaction means in plain words

Albuterol and Pazopanib can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.

Evidence level: Low

Why it happens

Additive QT prolongation, with beta-agonist-induced hypokalemia as a contributing factor.

What to do

Monitor ECG and serum potassium in patients with cardiac risk factors or heavy beta-agonist use. Use the lowest effective albuterol dose.

What to ask your pharmacist

  • Should I take them at different times of day?
  • Does the dose of either medicine need to change?
  • Is there anything I should avoid, such as alcohol or certain foods, while on both?

Bring a full list of your medicines, including over-the-counter products, supplements and herbal remedies, to every pharmacy visit.

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Frequently asked questions

Can I take Albuterol with Pazopanib?

MediHelp rates the interaction as moderate. Albuterol and Pazopanib can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Pazopanib can prolong the QT interval, and albuterol, particularly at high or systemic doses, may add to this through beta-agonist effects and hypokalemia. Together they may modestly raise arrhythmia risk.

How serious is the interaction between Albuterol and Pazopanib?

MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor ECG and serum potassium in patients with cardiac risk factors or heavy beta-agonist use. Use the lowest effective albuterol dose.

What other medicines interact with Pazopanib?

MediHelp also lists interactions of Pazopanib with, for example, Adagrasib, Amiodarone, Amisulpride. The full list is on the Pazopanib page.

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