Drug interactions
Pimozide + Somatropin
Severity: Minor
Pimozide and Somatropin: minor interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Growth hormone may increase CYP450 activity, which could slightly lower levels of CYP substrates such as pimozide. The evidence is limited and a clinical effect is unlikely to be marked.
What this interaction means in plain words
Pimozide and Somatropin have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Pimozide belongs to Central Nervous System; Somatropin belongs to Endocrine.
Why it happens
Possible modest induction of CYP-mediated metabolism by growth hormone.
What to do
No empirical dose change is needed; monitor clinical response to pimozide when somatropin is started or stopped.
What to ask your pharmacist
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
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Other interactions of Pimozide
- Adagrasib + Pimozide Contraindicated
- Amiodarone + Pimozide Contraindicated
- Amisulpride + Pimozide Contraindicated
- Amitriptyline + Pimozide Contraindicated
- Amoxapine + Pimozide Contraindicated
- Anagrelide + Pimozide Contraindicated
Other interactions of Somatropin
- Acarbose + Somatropin Moderate
- Albiglutide + Somatropin Moderate
- Alogliptin-metformin + Somatropin Moderate
- Alogliptin-pioglitazone + Somatropin Moderate
- Alogliptin + Somatropin Moderate
- Betamethasone + Somatropin Moderate
Frequently asked questions
Can I take Pimozide with Somatropin?
MediHelp rates the interaction as minor. Pimozide and Somatropin have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Growth hormone may increase CYP450 activity, which could slightly lower levels of CYP substrates such as pimozide. The evidence is limited and a clinical effect is unlikely to be marked.
How serious is the interaction between Pimozide and Somatropin?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: No empirical dose change is needed; monitor clinical response to pimozide when somatropin is started or stopped.
What other medicines interact with Pimozide?
MediHelp also lists interactions of Pimozide with, for example, Adagrasib, Amiodarone, Amisulpride. The full list is on the Pimozide page.
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