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Drug interactions

Pitavastatin + Telmisartan

Severity: Minor

Pitavastatin and Telmisartan: minor interaction.

Last updated

For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.

Summary

Telmisartan may inhibit OATP1B1 in vitro, which could theoretically raise pitavastatin exposure and myopathy risk. No clinically important interaction has been well established.

What this interaction means in plain words

Pitavastatin and Telmisartan have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.

Pitavastatin belongs to Cardiovascular; Telmisartan belongs to Cardiovascular.

Evidence level: Low

Why it happens

Possible OATP1B1 inhibition by telmisartan may reduce hepatic uptake of pitavastatin; this is largely theoretical.

What to do

No dose adjustment is routinely needed; advise patients to report unexplained muscle pain or weakness.

What to ask your pharmacist

  • Is there anything I should notice while taking both?
  • Do I need to tell my doctor at the next visit?

Bring a full list of your medicines, including over-the-counter products, supplements and herbal remedies, to every pharmacy visit.

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Frequently asked questions

Can I take Pitavastatin with Telmisartan?

MediHelp rates the interaction as minor. Pitavastatin and Telmisartan have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Telmisartan may inhibit OATP1B1 in vitro, which could theoretically raise pitavastatin exposure and myopathy risk. No clinically important interaction has been well established.

How serious is the interaction between Pitavastatin and Telmisartan?

MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: No dose adjustment is routinely needed; advise patients to report unexplained muscle pain or weakness.

What other medicines interact with Telmisartan?

MediHelp also lists interactions of Telmisartan with, for example, Aliskiren, Sparsentan, Amifostine. The full list is on the Telmisartan page.

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