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Drug interactions

Pyrantel pamoate + Theophylline

Severity: Minor

Pyrantel pamoate and Theophylline: minor interaction.

Last updated

For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.

Summary

Pyrantel has been reported to raise theophylline levels in isolated reports. The evidence is sparse and the mechanism is not established.

What this interaction means in plain words

Pyrantel pamoate and Theophylline have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.

Evidence level: Low

Why it happens

Mechanism not established; possible reduced theophylline clearance.

What to do

Monitor for signs of theophylline toxicity and check a serum level if symptoms appear.

What to ask your pharmacist

  • Is there anything I should notice while taking both?
  • Do I need to tell my doctor at the next visit?

Bring a full list of your medicines, including over-the-counter products, supplements and herbal remedies, to every pharmacy visit.

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Frequently asked questions

Can I take Pyrantel pamoate with Theophylline?

MediHelp rates the interaction as minor. Pyrantel pamoate and Theophylline have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Pyrantel has been reported to raise theophylline levels in isolated reports. The evidence is sparse and the mechanism is not established.

How serious is the interaction between Pyrantel pamoate and Theophylline?

MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor for signs of theophylline toxicity and check a serum level if symptoms appear.

What other medicines interact with Theophylline?

MediHelp also lists interactions of Theophylline with, for example, Riociguat, Adenosine, Apalutamide. The full list is on the Theophylline page.

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