Drug interactions
Albuterol + Quinine
Severity: Moderate
Albuterol and Quinine: moderate interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Albuterol can cause tachycardia, hypokalemia and modest QTc prolongation, while quinine prolongs the QT interval. Together they may increase the risk of arrhythmia, mainly with high or systemic albuterol doses.
What this interaction means in plain words
Albuterol and Quinine can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Why it happens
Additive QT prolongation, with beta-agonist induced hypokalemia.
What to do
Monitor potassium and ECG in patients with cardiac disease or when using high-dose or nebulized albuterol. Use the lowest effective bronchodilator dose.
What to ask your pharmacist
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
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Other interactions of Quinine
- Arsenic trioxide + Quinine Contraindicated
- Dofetilide + Quinine Contraindicated
- Dronedarone + Quinine Contraindicated
- Ibutilide + Quinine Contraindicated
- Mefloquine + Quinine Contraindicated
- Nilotinib + Quinine Contraindicated
Frequently asked questions
Can I take Albuterol with Quinine?
MediHelp rates the interaction as moderate. Albuterol and Quinine can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Albuterol can cause tachycardia, hypokalemia and modest QTc prolongation, while quinine prolongs the QT interval. Together they may increase the risk of arrhythmia, mainly with high or systemic albuterol doses.
How serious is the interaction between Albuterol and Quinine?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor potassium and ECG in patients with cardiac disease or when using high-dose or nebulized albuterol. Use the lowest effective bronchodilator dose.
What other medicines interact with Quinine?
MediHelp also lists interactions of Quinine with, for example, Arsenic trioxide, Dofetilide, Dronedarone. The full list is on the Quinine page.
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