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Drug interactions

Albuterol + Sunitinib

Severity: Moderate

Albuterol and Sunitinib: moderate interaction.

Last updated

For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.

Summary

Sunitinib can prolong the QT interval, and high doses of albuterol can cause hypokalemia, tachycardia and QT prolongation. Together they may raise arrhythmia risk, mainly with systemic or high-dose nebulized use.

What this interaction means in plain words

Albuterol and Sunitinib can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.

Evidence level: Low

Why it happens

Additive pharmacodynamic QT prolongation, with beta-agonist-induced hypokalemia contributing.

What to do

Monitor potassium and ECG in patients using frequent or high-dose albuterol, and correct hypokalemia. Occasional inhaled use at standard doses generally needs no change.

What to ask your pharmacist

  • Should I take them at different times of day?
  • Does the dose of either medicine need to change?
  • Is there anything I should avoid, such as alcohol or certain foods, while on both?

Bring a full list of your medicines, including over-the-counter products, supplements and herbal remedies, to every pharmacy visit.

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Frequently asked questions

Can I take Albuterol with Sunitinib?

MediHelp rates the interaction as moderate. Albuterol and Sunitinib can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Sunitinib can prolong the QT interval, and high doses of albuterol can cause hypokalemia, tachycardia and QT prolongation. Together they may raise arrhythmia risk, mainly with systemic or high-dose nebulized use.

How serious is the interaction between Albuterol and Sunitinib?

MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor potassium and ECG in patients using frequent or high-dose albuterol, and correct hypokalemia. Occasional inhaled use at standard doses generally needs no change.

What other medicines interact with Sunitinib?

MediHelp also lists interactions of Sunitinib with, for example, Adagrasib, Amiodarone, Amisulpride. The full list is on the Sunitinib page.

Full monographs, dosing and an interaction checker in the MediHelp app

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