Drug interactions
Sodium sulfate / potassium chloride / magnesium sulfate / polyethylene glycol + Telmisartan-amlodipine
Severity: Moderate
Sodium sulfate / potassium chloride / magnesium sulfate / polyethylene glycol and Telmisartan-amlodipine: moderate interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Bowel preparations cause fluid and electrolyte shifts and volume depletion. Combined with an ARB, this may increase the risk of acute kidney injury and electrolyte abnormalities. Hypotension from dehydration is also possible.
What this interaction means in plain words
Sodium sulfate / potassium chloride / magnesium sulfate / polyethylene glycol and Telmisartan-amlodipine can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Why it happens
Bowel-prep volume depletion and electrolyte shifts combined with ARB-reduced glomerular perfusion pressure and altered potassium handling.
What to do
Ensure adequate hydration during bowel preparation and consider withholding telmisartan on the day of preparation in at-risk patients. Check renal function and electrolytes if symptoms occur or in high-risk patients.
What to ask your pharmacist
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
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Other interactions of Telmisartan-amlodipine
- Aliskiren + Telmisartan-amlodipine Contraindicated
- Sparsentan + Telmisartan-amlodipine Contraindicated
- Amifostine + Telmisartan-amlodipine Major
- Amiloride + Telmisartan-amlodipine Major
- Benazepril + Telmisartan-amlodipine Major
- Candesartan + Telmisartan-amlodipine Major
Frequently asked questions
Can I take Sodium sulfate / potassium chloride / magnesium sulfate / polyethylene glycol with Telmisartan-amlodipine?
MediHelp rates the interaction as moderate. Sodium sulfate / potassium chloride / magnesium sulfate / polyethylene glycol and Telmisartan-amlodipine can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Bowel preparations cause fluid and electrolyte shifts and volume depletion. Combined with an ARB, this may increase the risk of acute kidney injury and electrolyte abnormalities. Hypotension from dehydration is also possible.
How serious is the interaction between Sodium sulfate / potassium chloride / magnesium sulfate / polyethylene glycol and Telmisartan-amlodipine?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Ensure adequate hydration during bowel preparation and consider withholding telmisartan on the day of preparation in at-risk patients. Check renal function and electrolytes if symptoms occur or in high-risk patients.
What other medicines interact with Telmisartan-amlodipine?
MediHelp also lists interactions of Telmisartan-amlodipine with, for example, Aliskiren, Sparsentan, Amifostine. The full list is on the Telmisartan-amlodipine page.
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