Drug interactions
Telmisartan-amlodipine + Umeclidinium bromide / vilanterol inhaled
Severity: Minor
Telmisartan-amlodipine and Umeclidinium bromide / vilanterol inhaled: minor interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Vilanterol, a beta-agonist, can lower serum potassium and prolong QT slightly, and this may be additive with thiazide-induced potassium loss. The effect is generally small at recommended inhaled doses, but may matter in patients with other risk factors.
What this interaction means in plain words
Telmisartan-amlodipine and Umeclidinium bromide / vilanterol inhaled have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Why it happens
Additive hypokalemia from beta-2 stimulated intracellular potassium shift and thiazide renal potassium wasting.
What to do
Monitor serum potassium in patients with heart disease, high doses or other hypokalemia risks. Keep the inhaler within the recommended dose.
What to ask your pharmacist
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
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Other interactions of Telmisartan-amlodipine
- Aliskiren + Telmisartan-amlodipine Contraindicated
- Sparsentan + Telmisartan-amlodipine Contraindicated
- Amifostine + Telmisartan-amlodipine Major
- Amiloride + Telmisartan-amlodipine Major
- Benazepril + Telmisartan-amlodipine Major
- Candesartan + Telmisartan-amlodipine Major
Frequently asked questions
Can I take Telmisartan-amlodipine with Umeclidinium bromide / vilanterol inhaled?
MediHelp rates the interaction as minor. Telmisartan-amlodipine and Umeclidinium bromide / vilanterol inhaled have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Vilanterol, a beta-agonist, can lower serum potassium and prolong QT slightly, and this may be additive with thiazide-induced potassium loss. The effect is generally small at recommended inhaled doses, but may matter in patients with other risk factors.
How serious is the interaction between Telmisartan-amlodipine and Umeclidinium bromide / vilanterol inhaled?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor serum potassium in patients with heart disease, high doses or other hypokalemia risks. Keep the inhaler within the recommended dose.
What other medicines interact with Telmisartan-amlodipine?
MediHelp also lists interactions of Telmisartan-amlodipine with, for example, Aliskiren, Sparsentan, Amifostine. The full list is on the Telmisartan-amlodipine page.
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