Drug interactions
Telmisartan-amlodipine + Vilanterol / fluticasone furoate inhaled
Severity: Minor
Telmisartan-amlodipine and Vilanterol / fluticasone furoate inhaled: minor interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Vilanterol can transiently lower serum potassium and may worsen ECG changes. Thiazide-induced potassium loss may add to this. The effect is usually modest with inhaled doses.
What this interaction means in plain words
Telmisartan-amlodipine and Vilanterol / fluticasone furoate inhaled have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Why it happens
Additive hypokalemia from beta-2 stimulated intracellular potassium shift and thiazide renal potassium wasting.
What to do
Monitor serum potassium in at-risk patients, such as those with cardiac disease or on other kaliuretic drugs. Do not exceed the recommended inhaler dose.
What to ask your pharmacist
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
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Other interactions of Telmisartan-amlodipine
- Aliskiren + Telmisartan-amlodipine Contraindicated
- Sparsentan + Telmisartan-amlodipine Contraindicated
- Amifostine + Telmisartan-amlodipine Major
- Amiloride + Telmisartan-amlodipine Major
- Benazepril + Telmisartan-amlodipine Major
- Candesartan + Telmisartan-amlodipine Major
Frequently asked questions
Can I take Telmisartan-amlodipine with Vilanterol / fluticasone furoate inhaled?
MediHelp rates the interaction as minor. Telmisartan-amlodipine and Vilanterol / fluticasone furoate inhaled have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Vilanterol can transiently lower serum potassium and may worsen ECG changes. Thiazide-induced potassium loss may add to this. The effect is usually modest with inhaled doses.
How serious is the interaction between Telmisartan-amlodipine and Vilanterol / fluticasone furoate inhaled?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor serum potassium in at-risk patients, such as those with cardiac disease or on other kaliuretic drugs. Do not exceed the recommended inhaler dose.
What other medicines interact with Telmisartan-amlodipine?
MediHelp also lists interactions of Telmisartan-amlodipine with, for example, Aliskiren, Sparsentan, Amifostine. The full list is on the Telmisartan-amlodipine page.
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