Drug interactions
Terbutaline + Xylometazoline
Severity: Minor
Terbutaline and Xylometazoline: minor interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Both agents are sympathomimetics, so combined use may add to increases in heart rate and blood pressure or cause tremor and palpitations. With intranasal xylometazoline the systemic contribution is usually small, so significant effects are mainly expected with overuse or in patients with cardiovascular disease.
What this interaction means in plain words
Terbutaline and Xylometazoline have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Terbutaline belongs to Respiratory; Xylometazoline belongs to Respiratory.
Why it happens
Additive adrenergic stimulation (alpha-agonist vasoconstriction plus beta2-agonist effects).
What to do
Use xylometazoline only at labeled doses and for a short duration. Monitor heart rate and blood pressure in patients with heart disease or hypertension.
What to ask your pharmacist
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
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Other interactions of Xylometazoline
- Selegiline + Xylometazoline Contraindicated
- Ergotamine + Xylometazoline Major
- Isocarboxazid + Xylometazoline Major
- Phenelzine + Xylometazoline Major
- Tranylcypromine + Xylometazoline Major
- Amitriptyline + Xylometazoline Moderate
Other interactions of Terbutaline
Frequently asked questions
Can I take Terbutaline with Xylometazoline?
MediHelp rates the interaction as minor. Terbutaline and Xylometazoline have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Both agents are sympathomimetics, so combined use may add to increases in heart rate and blood pressure or cause tremor and palpitations. With intranasal xylometazoline the systemic contribution is usually small, so significant effects are mainly expected with overuse or in patients with cardiovascular disease.
How serious is the interaction between Terbutaline and Xylometazoline?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Use xylometazoline only at labeled doses and for a short duration. Monitor heart rate and blood pressure in patients with heart disease or hypertension.
What other medicines interact with Xylometazoline?
MediHelp also lists interactions of Xylometazoline with, for example, Selegiline, Ergotamine, Isocarboxazid. The full list is on the Xylometazoline page.
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