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تداخل‌های دارویی

Abacavir + Methadone

شدت: جزئی

Abacavir and Methadone: minor interaction.

آخرین به‌روزرسانی

ویژه کادر درمان — فقط جهت مرجع. این صفحه خلاصه‌ای کوتاه است، توصیه پزشکی نیست و جایگزین بروشور رسمی یا قضاوت بالینی نمی‌شود. پیش از تجویز یا تحویل دارو همیشه بررسی کنید.

محتوای بالینی این صفحه فقط به زبان انگلیسی موجود است.

خلاصه

Abacavir may modestly increase methadone clearance, which could occasionally lead to reduced opioid effect or withdrawal symptoms. In studies the changes in methadone exposure were small and dose adjustment was generally not needed.

معنای این تداخل به زبان ساده

Abacavir and Methadone have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.

Abacavir belongs to Anti Virals; Methadone belongs to Musculoskeletal.

سطح شواهد: Moderate

چرا رخ می‌دهد

Possible modest increase in methadone clearance; the exact mechanism is not established.

اقدام لازم

Monitor for withdrawal symptoms or reduced effect after starting abacavir and increase the methadone dose only if clinically needed.

از داروساز چه بپرسید

  • Is there anything I should notice while taking both?
  • Do I need to tell my doctor at the next visit?

Bring a full list of your medicines, including over-the-counter products, supplements and herbal remedies, to every pharmacy visit.

ویژه اعضای Pro+

باز کردن کل صفحه

یک حساب بسازید و دوره آزمایشی Pro+ را شروع کنید تا توصیه‌های کامل مدیریت Abacavir و Methadone، یادداشت‌های تکمیلی، جزئیات شواهد و بررسی‌کننده تداخل برای کل نسخه را باز کنید.

  • Full clinical management advice
  • Additional notes
  • Evidence detail
  • Interaction checker for a whole prescription

Pro+ را ۱۴ روز رایگان در وب امتحان کنید. بدون نیاز به کارت.

پرسش‌های متداول

Can I take Abacavir with Methadone?

MediHelp rates the interaction as minor. Abacavir and Methadone have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Abacavir may modestly increase methadone clearance, which could occasionally lead to reduced opioid effect or withdrawal symptoms. In studies the changes in methadone exposure were small and dose adjustment was generally not needed.

How serious is the interaction between Abacavir and Methadone?

MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor for withdrawal symptoms or reduced effect after starting abacavir and increase the methadone dose only if clinically needed.

What other medicines interact with Methadone?

MediHelp also lists interactions of Methadone with, for example, Alvimopan, Calcium / magnesium / potassium / sodium oxybates, Droperidol. The full list is on the Methadone page.

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