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تداخل‌های دارویی

Adenovirus types 4 and 7 live + Certolizumab pegol

شدت: منع مصرف

Adenovirus types 4 and 7 live and Certolizumab pegol: contraindicated interaction.

آخرین به‌روزرسانی

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محتوای بالینی این صفحه فقط به زبان انگلیسی موجود است.

خلاصه

The oral adenovirus type 4 and 7 vaccine contains live virus. Under TNF blockade with certolizumab, replication may be poorly controlled, risking vaccine-related infection and a reduced immune response.

معنای این تداخل به زبان ساده

Adenovirus types 4 and 7 live and Certolizumab pegol are not normally used together. Taking them at the same time is expected to cause harm or make one of them unsafe, so a different medicine is usually chosen for one of the two.

سطح شواهد: Low

چرا رخ می‌دهد

TNF inhibition impairs immune control of live attenuated virus, raising infection risk and reducing vaccine response.

اقدام لازم

Avoid this live vaccine during certolizumab therapy. Vaccinate before starting treatment if indicated, allowing at least 4 weeks.

از داروساز چه بپرسید

  • Is there an alternative to one of these two medicines for me?
  • If both are essential, who is monitoring me and how often?
  • Which symptoms mean I should stop and seek help straight away?

Bring a full list of your medicines, including over-the-counter products, supplements and herbal remedies, to every pharmacy visit.

ویژه اعضای Pro+

باز کردن کل صفحه

یک حساب بسازید و دوره آزمایشی Pro+ را شروع کنید تا توصیه‌های کامل مدیریت Adenovirus types 4 and 7 live و Certolizumab pegol، یادداشت‌های تکمیلی، جزئیات شواهد و بررسی‌کننده تداخل برای کل نسخه را باز کنید.

  • Full clinical management advice
  • Additional notes
  • Evidence detail
  • Interaction checker for a whole prescription

Pro+ را ۱۴ روز رایگان در وب امتحان کنید. بدون نیاز به کارت.

پرسش‌های متداول

Can I take Adenovirus types 4 and 7 live with Certolizumab pegol?

MediHelp rates the interaction as contraindicated. Adenovirus types 4 and 7 live and Certolizumab pegol are not normally used together. Taking them at the same time is expected to cause harm or make one of them unsafe, so a different medicine is usually chosen for one of the two. The oral adenovirus type 4 and 7 vaccine contains live virus. Under TNF blockade with certolizumab, replication may be poorly controlled, risking vaccine-related infection and a reduced immune response.

How serious is the interaction between Adenovirus types 4 and 7 live and Certolizumab pegol?

MediHelp rates it contraindicated, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Avoid this live vaccine during certolizumab therapy. Vaccinate before starting treatment if indicated, allowing at least 4 weeks.

What other medicines interact with Certolizumab pegol?

MediHelp also lists interactions of Certolizumab pegol with, for example, Bcg intravesical live, Bcg vaccine live, Influenza virus vaccine quadrivalent intranasal. The full list is on the Certolizumab pegol page.

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