تداخل‌های دارویی
Adenovirus types 4 and 7 live + Dacarbazine
شدت: شدید
Adenovirus types 4 and 7 live and Dacarbazine: major interaction.
آخرین به‌روزرسانی
ویژه کادر درمان — فقط جهت مرجع. این صفحه خلاصه‌ای کوتاه است، توصیه پزشکی نیست و جایگزین بروشور رسمی یا قضاوت بالینی نمی‌شود. پیش از تجویز یا تحویل دارو همیشه بررسی کنید.
محتوای بالینی این صفحه فقط به زبان انگلیسی موجود است.
خلاصه
Dacarbazine causes immunosuppression, so a live oral adenovirus vaccine may fail to produce protective immunity and the vaccine virus may replicate and cause disease. Live vaccines are generally avoided in patients on myelosuppressive chemotherapy.
معنای این تداخل به زبان ساده
Adenovirus types 4 and 7 live and Dacarbazine can interact in a way that may be serious. Using them together is sometimes necessary, but it needs a deliberate decision by the prescriber, a plan for monitoring, and clear advice on the warning signs to watch for.
چرا رخ می‌دهد
Chemotherapy-induced immunosuppression impairs vaccine response and permits uncontrolled replication of live attenuated virus.
اقدام لازم
Avoid live vaccines during chemotherapy and for at least 3 months after stopping. Use alternatives or defer vaccination until immune recovery.
از داروساز چه بپرسید
- Does the benefit of taking both outweigh the risk in my case?
- Do I need any blood test, ECG or other check while on both?
- What early warning signs should I watch for, and what should I do if they appear?
ویژه اعضای Pro+
باز کردن کل صفحه
یک حساب بسازید و دوره آزمایشی Pro+ را شروع کنید تا توصیه‌های کامل مدیریت Adenovirus types 4 and 7 live و Dacarbazine، یادداشت‌های تکمیلی، جزئیات شواهد و بررسی‌کننده تداخل برای کل نسخه را باز کنید.
- Full clinical management advice
- Additional notes
- Evidence detail
- Interaction checker for a whole prescription
Pro+ را ۱۴ روز رایگان در وب امتحان کنید. بدون نیاز به کارت.
تداخلات دیگر Dacarbazine
پرسش‌های متداول
Can I take Adenovirus types 4 and 7 live with Dacarbazine?
MediHelp rates the interaction as major. Adenovirus types 4 and 7 live and Dacarbazine can interact in a way that may be serious. Using them together is sometimes necessary, but it needs a deliberate decision by the prescriber, a plan for monitoring, and clear advice on the warning signs to watch for. Dacarbazine causes immunosuppression, so a live oral adenovirus vaccine may fail to produce protective immunity and the vaccine virus may replicate and cause disease. Live vaccines are generally avoided in patients on myelosuppressive chemotherapy.
How serious is the interaction between Adenovirus types 4 and 7 live and Dacarbazine?
MediHelp rates it major, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Avoid live vaccines during chemotherapy and for at least 3 months after stopping. Use alternatives or defer vaccination until immune recovery.
What other medicines interact with Dacarbazine?
MediHelp also lists interactions of Dacarbazine with, for example, Axicabtagene ciloleucel, Belatacept, Brexucabtagene autoleucel. The full list is on the Dacarbazine page.
تک‌نگاری کامل، دوزاژ و بررسی تداخل دارویی در برنامه MediHelp
مرجع کامل را باز کنید، تداخل چند دارو را بررسی کنید و از ابزارهای دوز در برنامه MediHelp استفاده کنید.
