تداخل‌های دارویی
Adenovirus types 4 and 7 live + Doxorubicin
شدت: شدید
Adenovirus types 4 and 7 live and Doxorubicin: major interaction.
آخرین به‌روزرسانی
ویژه کادر درمان — فقط جهت مرجع. این صفحه خلاصه‌ای کوتاه است، توصیه پزشکی نیست و جایگزین بروشور رسمی یا قضاوت بالینی نمی‌شود. پیش از تجویز یا تحویل دارو همیشه بررسی کنید.
محتوای بالینی این صفحه فقط به زبان انگلیسی موجود است.
خلاصه
Doxorubicin causes myelosuppression and immunosuppression, which can blunt the response to the live oral adenovirus vaccine. The attenuated virus may also replicate more extensively in an immunocompromised patient, raising the risk of vaccine-related infection.
معنای این تداخل به زبان ساده
Adenovirus types 4 and 7 live and Doxorubicin can interact in a way that may be serious. Using them together is sometimes necessary, but it needs a deliberate decision by the prescriber, a plan for monitoring, and clear advice on the warning signs to watch for.
چرا رخ می‌دهد
Cytotoxic immunosuppression impairs vaccine immune response and permits uncontrolled replication of the live attenuated virus.
اقدام لازم
Avoid live vaccines during chemotherapy and for at least 3 months after it ends, or until immune recovery is confirmed. Use non-live vaccines where an alternative exists.
از داروساز چه بپرسید
- Does the benefit of taking both outweigh the risk in my case?
- Do I need any blood test, ECG or other check while on both?
- What early warning signs should I watch for, and what should I do if they appear?
ویژه اعضای Pro+
باز کردن کل صفحه
یک حساب بسازید و دوره آزمایشی Pro+ را شروع کنید تا توصیه‌های کامل مدیریت Adenovirus types 4 and 7 live و Doxorubicin، یادداشت‌های تکمیلی، جزئیات شواهد و بررسی‌کننده تداخل برای کل نسخه را باز کنید.
- Full clinical management advice
- Additional notes
- Evidence detail
- Interaction checker for a whole prescription
Pro+ را ۱۴ روز رایگان در وب امتحان کنید. بدون نیاز به کارت.
تداخلات دیگر Doxorubicin
پرسش‌های متداول
Can I take Adenovirus types 4 and 7 live with Doxorubicin?
MediHelp rates the interaction as major. Adenovirus types 4 and 7 live and Doxorubicin can interact in a way that may be serious. Using them together is sometimes necessary, but it needs a deliberate decision by the prescriber, a plan for monitoring, and clear advice on the warning signs to watch for. Doxorubicin causes myelosuppression and immunosuppression, which can blunt the response to the live oral adenovirus vaccine. The attenuated virus may also replicate more extensively in an immunocompromised patient, raising the risk of vaccine-related infection.
How serious is the interaction between Adenovirus types 4 and 7 live and Doxorubicin?
MediHelp rates it major, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Avoid live vaccines during chemotherapy and for at least 3 months after it ends, or until immune recovery is confirmed. Use non-live vaccines where an alternative exists.
What other medicines interact with Doxorubicin?
MediHelp also lists interactions of Doxorubicin with, for example, Belatacept, Cobicistat, Cyclophosphamide. The full list is on the Doxorubicin page.
تک‌نگاری کامل، دوزاژ و بررسی تداخل دارویی در برنامه MediHelp
مرجع کامل را باز کنید، تداخل چند دارو را بررسی کنید و از ابزارهای دوز در برنامه MediHelp استفاده کنید.
