تداخل‌های دارویی
Adenovirus types 4 and 7 live + Fludarabine
شدت: منع مصرف
Adenovirus types 4 and 7 live and Fludarabine: contraindicated interaction.
آخرین به‌روزرسانی
ویژه کادر درمان — فقط جهت مرجع. این صفحه خلاصه‌ای کوتاه است، توصیه پزشکی نیست و جایگزین بروشور رسمی یا قضاوت بالینی نمی‌شود. پیش از تجویز یا تحویل دارو همیشه بررسی کنید.
محتوای بالینی این صفحه فقط به زبان انگلیسی موجود است.
خلاصه
Fludarabine causes profound and prolonged lymphopenia. A live oral adenovirus vaccine could replicate unchecked and cause disseminated vaccine-strain infection, and the vaccine response would also be poor.
معنای این تداخل به زبان ساده
Adenovirus types 4 and 7 live and Fludarabine are not normally used together. Taking them at the same time is expected to cause harm or make one of them unsafe, so a different medicine is usually chosen for one of the two.
چرا رخ می‌دهد
Fludarabine-induced immunosuppression impairs control of live attenuated virus replication and reduces vaccine immunogenicity.
اقدام لازم
Do not give this live vaccine during fludarabine therapy. Defer vaccination until immune recovery is confirmed, usually at least 3 months after therapy ends.
از داروساز چه بپرسید
- Is there an alternative to one of these two medicines for me?
- If both are essential, who is monitoring me and how often?
- Which symptoms mean I should stop and seek help straight away?
ویژه اعضای Pro+
باز کردن کل صفحه
یک حساب بسازید و دوره آزمایشی Pro+ را شروع کنید تا توصیه‌های کامل مدیریت Adenovirus types 4 and 7 live و Fludarabine، یادداشت‌های تکمیلی، جزئیات شواهد و بررسی‌کننده تداخل برای کل نسخه را باز کنید.
- Full clinical management advice
- Additional notes
- Evidence detail
- Interaction checker for a whole prescription
Pro+ را ۱۴ روز رایگان در وب امتحان کنید. بدون نیاز به کارت.
تداخلات دیگر Fludarabine
پرسش‌های متداول
Can I take Adenovirus types 4 and 7 live with Fludarabine?
MediHelp rates the interaction as contraindicated. Adenovirus types 4 and 7 live and Fludarabine are not normally used together. Taking them at the same time is expected to cause harm or make one of them unsafe, so a different medicine is usually chosen for one of the two. Fludarabine causes profound and prolonged lymphopenia. A live oral adenovirus vaccine could replicate unchecked and cause disseminated vaccine-strain infection, and the vaccine response would also be poor.
How serious is the interaction between Adenovirus types 4 and 7 live and Fludarabine?
MediHelp rates it contraindicated, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Do not give this live vaccine during fludarabine therapy. Defer vaccination until immune recovery is confirmed, usually at least 3 months after therapy ends.
What other medicines interact with Fludarabine?
MediHelp also lists interactions of Fludarabine with, for example, Pentostatin, Belatacept, Dengue vaccine. The full list is on the Fludarabine page.
تک‌نگاری کامل، دوزاژ و بررسی تداخل دارویی در برنامه MediHelp
مرجع کامل را باز کنید، تداخل چند دارو را بررسی کنید و از ابزارهای دوز در برنامه MediHelp استفاده کنید.
