تداخل‌های دارویی
Adenovirus types 4 and 7 live + Fluorouracil
شدت: شدید
Adenovirus types 4 and 7 live and Fluorouracil: major interaction.
آخرین به‌روزرسانی
ویژه کادر درمان — فقط جهت مرجع. این صفحه خلاصه‌ای کوتاه است، توصیه پزشکی نیست و جایگزین بروشور رسمی یا قضاوت بالینی نمی‌شود. پیش از تجویز یا تحویل دارو همیشه بررسی کنید.
محتوای بالینی این صفحه فقط به زبان انگلیسی موجود است.
خلاصه
Fluorouracil causes myelosuppression and immunosuppression, so a live oral adenovirus vaccine may replicate excessively and cause disease. The vaccine response may also be blunted.
معنای این تداخل به زبان ساده
Adenovirus types 4 and 7 live and Fluorouracil can interact in a way that may be serious. Using them together is sometimes necessary, but it needs a deliberate decision by the prescriber, a plan for monitoring, and clear advice on the warning signs to watch for.
چرا رخ می‌دهد
Cytotoxic immunosuppression impairs control of live-attenuated virus and reduces vaccine immunogenicity.
اقدام لازم
Do not give the live vaccine during chemotherapy; defer vaccination until at least about 3 months after chemotherapy ends and immune recovery is confirmed.
از داروساز چه بپرسید
- Does the benefit of taking both outweigh the risk in my case?
- Do I need any blood test, ECG or other check while on both?
- What early warning signs should I watch for, and what should I do if they appear?
ویژه اعضای Pro+
باز کردن کل صفحه
یک حساب بسازید و دوره آزمایشی Pro+ را شروع کنید تا توصیه‌های کامل مدیریت Adenovirus types 4 and 7 live و Fluorouracil، یادداشت‌های تکمیلی، جزئیات شواهد و بررسی‌کننده تداخل برای کل نسخه را باز کنید.
- Full clinical management advice
- Additional notes
- Evidence detail
- Interaction checker for a whole prescription
Pro+ را ۷ روز رایگان در وب امتحان کنید. بدون نیاز به کارت.
تداخلات دیگر Fluorouracil
پرسش‌های متداول
Can I take Adenovirus types 4 and 7 live with Fluorouracil?
MediHelp rates the interaction as major. Adenovirus types 4 and 7 live and Fluorouracil can interact in a way that may be serious. Using them together is sometimes necessary, but it needs a deliberate decision by the prescriber, a plan for monitoring, and clear advice on the warning signs to watch for. Fluorouracil causes myelosuppression and immunosuppression, so a live oral adenovirus vaccine may replicate excessively and cause disease. The vaccine response may also be blunted.
How serious is the interaction between Adenovirus types 4 and 7 live and Fluorouracil?
MediHelp rates it major, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Do not give the live vaccine during chemotherapy; defer vaccination until at least about 3 months after chemotherapy ends and immune recovery is confirmed.
What other medicines interact with Fluorouracil?
MediHelp also lists interactions of Fluorouracil with, for example, Axicabtagene ciloleucel, Belatacept, Brexucabtagene autoleucel. The full list is on the Fluorouracil page.
تک‌نگاری کامل، دوزاژ و بررسی تداخل دارویی در برنامه MediHelp
مرجع کامل را باز کنید، تداخل چند دارو را بررسی کنید و از ابزارهای دوز در برنامه MediHelp استفاده کنید.
