تداخلهای دارویی
Adenovirus types 4 and 7 live + Paclitaxel
شدت: شدید
Adenovirus types 4 and 7 live and Paclitaxel: major interaction.
آخرین بهروزرسانی
ویژه کادر درمان — فقط جهت مرجع. این صفحه خلاصهای کوتاه است، توصیه پزشکی نیست و جایگزین بروشور رسمی یا قضاوت بالینی نمیشود. پیش از تجویز یا تحویل دارو همیشه بررسی کنید.
محتوای بالینی این صفحه فقط به زبان انگلیسی موجود است.
خلاصه
Paclitaxel is myelosuppressive and immunosuppressive, so a live oral adenovirus vaccine may cause disseminated vaccine-strain infection. The immune response to the vaccine may also be diminished.
معنای این تداخل به زبان ساده
Adenovirus types 4 and 7 live and Paclitaxel can interact in a way that may be serious. Using them together is sometimes necessary, but it needs a deliberate decision by the prescriber, a plan for monitoring, and clear advice on the warning signs to watch for.
چرا رخ میدهد
Chemotherapy-induced immunosuppression impairs control of live attenuated virus replication and reduces vaccine immunogenicity.
اقدام لازم
Avoid the live vaccine during paclitaxel therapy and for at least 3 months after it ends. Consider vaccinating only after immune recovery.
از داروساز چه بپرسید
- Does the benefit of taking both outweigh the risk in my case?
- Do I need any blood test, ECG or other check while on both?
- What early warning signs should I watch for, and what should I do if they appear?
ویژه اعضای Pro+
باز کردن کل صفحه
یک حساب بسازید و دوره آزمایشی Pro+ را شروع کنید تا توصیههای کامل مدیریت Adenovirus types 4 and 7 live و Paclitaxel، یادداشتهای تکمیلی، جزئیات شواهد و بررسیکننده تداخل برای کل نسخه را باز کنید.
- Full clinical management advice
- Additional notes
- Evidence detail
- Interaction checker for a whole prescription
Pro+ را ۱۴ روز رایگان در وب امتحان کنید. بدون نیاز به کارت.
تداخلات دیگر Paclitaxel
پرسشهای متداول
Can I take Adenovirus types 4 and 7 live with Paclitaxel?
MediHelp rates the interaction as major. Adenovirus types 4 and 7 live and Paclitaxel can interact in a way that may be serious. Using them together is sometimes necessary, but it needs a deliberate decision by the prescriber, a plan for monitoring, and clear advice on the warning signs to watch for. Paclitaxel is myelosuppressive and immunosuppressive, so a live oral adenovirus vaccine may cause disseminated vaccine-strain infection. The immune response to the vaccine may also be diminished.
How serious is the interaction between Adenovirus types 4 and 7 live and Paclitaxel?
MediHelp rates it major, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Avoid the live vaccine during paclitaxel therapy and for at least 3 months after it ends. Consider vaccinating only after immune recovery.
What other medicines interact with Paclitaxel?
MediHelp also lists interactions of Paclitaxel with, for example, Cobicistat, Cyclosporine, Cyclosporin. The full list is on the Paclitaxel page.
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