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تداخل‌های دارویی

Allogeneic cultured keratinocytes and fibroblasts + Silver sulfadiazine

شدت: متوسط

Allogeneic cultured keratinocytes and fibroblasts and Silver sulfadiazine: moderate interaction.

آخرین به‌روزرسانی

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محتوای بالینی این صفحه فقط به زبان انگلیسی موجود است.

خلاصه

Silver sulfadiazine applied to a wound leaves silver ions that are toxic to living cells. This can reduce the viability of the cultured keratinocytes and fibroblasts in the cell-based skin product and impair graft take.

معنای این تداخل به زبان ساده

Allogeneic cultured keratinocytes and fibroblasts and Silver sulfadiazine can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.

سطح شواهد: Low

چرا رخ می‌دهد

Local cytotoxicity of silver ions toward cultured human keratinocytes and fibroblasts.

اقدام لازم

Do not apply silver sulfadiazine or silver dressings to the site before or at the time of application of the cellular product. Rinse the wound bed thoroughly if silver was previously used.

از داروساز چه بپرسید

  • Should I take them at different times of day?
  • Does the dose of either medicine need to change?
  • Is there anything I should avoid, such as alcohol or certain foods, while on both?

Bring a full list of your medicines, including over-the-counter products, supplements and herbal remedies, to every pharmacy visit.

ویژه اعضای Pro+

باز کردن کل صفحه

یک حساب بسازید و دوره آزمایشی Pro+ را شروع کنید تا توصیه‌های کامل مدیریت Allogeneic cultured keratinocytes and fibroblasts و Silver sulfadiazine، یادداشت‌های تکمیلی، جزئیات شواهد و بررسی‌کننده تداخل برای کل نسخه را باز کنید.

  • Full clinical management advice
  • Additional notes
  • Evidence detail
  • Interaction checker for a whole prescription

Pro+ را ۱۴ روز رایگان در وب امتحان کنید. بدون نیاز به کارت.

پرسش‌های متداول

Can I take Allogeneic cultured keratinocytes and fibroblasts with Silver sulfadiazine?

MediHelp rates the interaction as moderate. Allogeneic cultured keratinocytes and fibroblasts and Silver sulfadiazine can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Silver sulfadiazine applied to a wound leaves silver ions that are toxic to living cells. This can reduce the viability of the cultured keratinocytes and fibroblasts in the cell-based skin product and impair graft take.

How serious is the interaction between Allogeneic cultured keratinocytes and fibroblasts and Silver sulfadiazine?

MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Do not apply silver sulfadiazine or silver dressings to the site before or at the time of application of the cellular product. Rinse the wound bed thoroughly if silver was previously used.

What other medicines interact with Silver sulfadiazine?

MediHelp also lists interactions of Silver sulfadiazine with, for example, Collagenase, Papain, Trypsin. The full list is on the Silver sulfadiazine page.

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