تداخل‌های دارویی
Allopurinol + Amlodipine-perindopril
شدت: متوسط
Allopurinol and Amlodipine-perindopril: moderate interaction.
آخرین به‌روزرسانی
ویژه کادر درمان — فقط جهت مرجع. این صفحه خلاصه‌ای کوتاه است، توصیه پزشکی نیست و جایگزین بروشور رسمی یا قضاوت بالینی نمی‌شود. پیش از تجویز یا تحویل دارو همیشه بررسی کنید.
محتوای بالینی این صفحه فقط به زبان انگلیسی موجود است.
خلاصه
ACE inhibitors given with allopurinol have been associated with hypersensitivity reactions, including rare severe skin reactions. The evidence is limited to case reports and the mechanism is unclear.
معنای این تداخل به زبان ساده
Allopurinol and Amlodipine-perindopril can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Allopurinol belongs to Genitourinary; Amlodipine-perindopril belongs to Cardiovascular.
چرا رخ می‌دهد
The mechanism is not established; an additive hypersensitivity or immune-mediated effect has been proposed.
اقدام لازم
Counsel patients to report rash, fever or mucosal lesions promptly and stop allopurinol if these occur. Monitor renal function, as allopurinol dose may need adjustment.
از داروساز چه بپرسید
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
ویژه اعضای Pro+
باز کردن کل صفحه
یک حساب بسازید و دوره آزمایشی Pro+ را شروع کنید تا توصیه‌های کامل مدیریت Allopurinol و Amlodipine-perindopril، یادداشت‌های تکمیلی، جزئیات شواهد و بررسی‌کننده تداخل برای کل نسخه را باز کنید.
- Full clinical management advice
- Additional notes
- Evidence detail
- Interaction checker for a whole prescription
Pro+ را ۱۴ روز رایگان در وب امتحان کنید. بدون نیاز به کارت.
تداخلات دیگر Amlodipine-perindopril
تداخلات دیگر Allopurinol
پرسش‌های متداول
Can I take Allopurinol with Amlodipine-perindopril?
MediHelp rates the interaction as moderate. Allopurinol and Amlodipine-perindopril can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. ACE inhibitors given with allopurinol have been associated with hypersensitivity reactions, including rare severe skin reactions. The evidence is limited to case reports and the mechanism is unclear.
How serious is the interaction between Allopurinol and Amlodipine-perindopril?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Counsel patients to report rash, fever or mucosal lesions promptly and stop allopurinol if these occur. Monitor renal function, as allopurinol dose may need adjustment.
What other medicines interact with Amlodipine-perindopril?
MediHelp also lists interactions of Amlodipine-perindopril with, for example, Aliskiren, Protein a column, Sacubitril / valsartan. The full list is on the Amlodipine-perindopril page.
تک‌نگاری کامل، دوزاژ و بررسی تداخل دارویی در برنامه MediHelp
مرجع کامل را باز کنید، تداخل چند دارو را بررسی کنید و از ابزارهای دوز در برنامه MediHelp استفاده کنید.
