تداخل‌های دارویی
Alogliptin-pioglitazone + Bexarotene
شدت: متوسط
Alogliptin-pioglitazone and Bexarotene: moderate interaction.
آخرین به‌روزرسانی
ویژه کادر درمان — فقط جهت مرجع. این صفحه خلاصه‌ای کوتاه است، توصیه پزشکی نیست و جایگزین بروشور رسمی یا قضاوت بالینی نمی‌شود. پیش از تجویز یا تحویل دارو همیشه بررسی کنید.
محتوای بالینی این صفحه فقط به زبان انگلیسی موجود است.
خلاصه
Bexarotene acts on retinoid X receptors, which are the heterodimer partners of PPAR-gamma, and may enhance the insulin-sensitizing effect of pioglitazone. Hypoglycemia is possible, and bexarotene also commonly causes hyperlipidemia and hypothyroidism that can affect metabolic control.
معنای این تداخل به زبان ساده
Alogliptin-pioglitazone and Bexarotene can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Alogliptin-pioglitazone belongs to Endocrine; Bexarotene belongs to Oncology.
چرا رخ می‌دهد
Additive activation of the PPAR-gamma/RXR pathway enhances insulin sensitization.
اقدام لازم
Monitor blood glucose when starting bexarotene and reduce antidiabetic doses if hypoglycemia occurs.
از داروساز چه بپرسید
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
ویژه اعضای Pro+
باز کردن کل صفحه
یک حساب بسازید و دوره آزمایشی Pro+ را شروع کنید تا توصیه‌های کامل مدیریت Alogliptin-pioglitazone و Bexarotene، یادداشت‌های تکمیلی، جزئیات شواهد و بررسی‌کننده تداخل برای کل نسخه را باز کنید.
- Full clinical management advice
- Additional notes
- Evidence detail
- Interaction checker for a whole prescription
Pro+ را ۷ روز رایگان در وب امتحان کنید. بدون نیاز به کارت.
تداخلات دیگر Alogliptin-pioglitazone
تداخلات دیگر Bexarotene
- Bexarotene + Gemfibrozil شدید
- Bexarotene + Lorlatinib شدید
- Amobarbital + Bexarotene متوسط
- Aprepitant + Bexarotene متوسط
- Axitinib + Bexarotene متوسط
- Bexarotene + Bosentan متوسط
پرسش‌های متداول
Can I take Alogliptin-pioglitazone with Bexarotene?
MediHelp rates the interaction as moderate. Alogliptin-pioglitazone and Bexarotene can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Bexarotene acts on retinoid X receptors, which are the heterodimer partners of PPAR-gamma, and may enhance the insulin-sensitizing effect of pioglitazone. Hypoglycemia is possible, and bexarotene also commonly causes hyperlipidemia and hypothyroidism that can affect metabolic control.
How serious is the interaction between Alogliptin-pioglitazone and Bexarotene?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor blood glucose when starting bexarotene and reduce antidiabetic doses if hypoglycemia occurs.
What other medicines interact with Alogliptin-pioglitazone?
MediHelp also lists interactions of Alogliptin-pioglitazone with, for example, Gemfibrozil, Insulin aspart, Insulin degludec. The full list is on the Alogliptin-pioglitazone page.
تک‌نگاری کامل، دوزاژ و بررسی تداخل دارویی در برنامه MediHelp
مرجع کامل را باز کنید، تداخل چند دارو را بررسی کنید و از ابزارهای دوز در برنامه MediHelp استفاده کنید.
