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تداخل‌های دارویی

Alogliptin-pioglitazone + Somatrogon

شدت: متوسط

Alogliptin-pioglitazone and Somatrogon: moderate interaction.

آخرین به‌روزرسانی

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محتوای بالینی این صفحه فقط به زبان انگلیسی موجود است.

خلاصه

Somatrogon, a long-acting growth hormone, can lower insulin sensitivity and raise blood glucose, reducing the efficacy of antidiabetic drugs. Patients with diabetes may need treatment intensification.

معنای این تداخل به زبان ساده

Alogliptin-pioglitazone and Somatrogon can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.

Alogliptin-pioglitazone belongs to Endocrine; Somatrogon belongs to Endocrine.

سطح شواهد: Moderate

چرا رخ می‌دهد

Growth hormone induces insulin resistance, opposing the glucose-lowering effect of pioglitazone and alogliptin.

اقدام لازم

Monitor blood glucose and HbA1c when somatrogon is started or the dose changed, and adjust antidiabetic doses accordingly.

از داروساز چه بپرسید

  • Should I take them at different times of day?
  • Does the dose of either medicine need to change?
  • Is there anything I should avoid, such as alcohol or certain foods, while on both?

Bring a full list of your medicines, including over-the-counter products, supplements and herbal remedies, to every pharmacy visit.

ویژه اعضای Pro+

باز کردن کل صفحه

یک حساب بسازید و دوره آزمایشی Pro+ را شروع کنید تا توصیه‌های کامل مدیریت Alogliptin-pioglitazone و Somatrogon، یادداشت‌های تکمیلی، جزئیات شواهد و بررسی‌کننده تداخل برای کل نسخه را باز کنید.

  • Full clinical management advice
  • Additional notes
  • Evidence detail
  • Interaction checker for a whole prescription

Pro+ را ۱۴ روز رایگان در وب امتحان کنید. بدون نیاز به کارت.

پرسش‌های متداول

Can I take Alogliptin-pioglitazone with Somatrogon?

MediHelp rates the interaction as moderate. Alogliptin-pioglitazone and Somatrogon can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Somatrogon, a long-acting growth hormone, can lower insulin sensitivity and raise blood glucose, reducing the efficacy of antidiabetic drugs. Patients with diabetes may need treatment intensification.

How serious is the interaction between Alogliptin-pioglitazone and Somatrogon?

MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor blood glucose and HbA1c when somatrogon is started or the dose changed, and adjust antidiabetic doses accordingly.

What other medicines interact with Alogliptin-pioglitazone?

MediHelp also lists interactions of Alogliptin-pioglitazone with, for example, Gemfibrozil, Insulin aspart, Insulin degludec. The full list is on the Alogliptin-pioglitazone page.

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