تداخل‌های دارویی
Amikacin + Cefuroxime
شدت: متوسط
Amikacin and Cefuroxime: moderate interaction.
آخرین به‌روزرسانی
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خلاصه
Cefuroxime given with amikacin may increase the risk of kidney injury, especially in older, dehydrated or renally impaired patients. Amikacin is the principal nephrotoxic and ototoxic agent, and the combination is often used on purpose in serious infections.
معنای این تداخل به زبان ساده
Amikacin and Cefuroxime can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Amikacin belongs to Anti Bacterial; Cefuroxime belongs to Anti Bacterial.
چرا رخ می‌دهد
Additive nephrotoxic potential; cephalosporins may modestly add to aminoglycoside tubular injury.
اقدام لازم
Monitor serum creatinine and amikacin levels, keep the patient hydrated and limit the aminoglycoside duration. Adjust the doses for renal function.
از داروساز چه بپرسید
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
ویژه اعضای Pro+
باز کردن کل صفحه
یک حساب بسازید و دوره آزمایشی Pro+ را شروع کنید تا توصیه‌های کامل مدیریت Amikacin و Cefuroxime، یادداشت‌های تکمیلی، جزئیات شواهد و بررسی‌کننده تداخل برای کل نسخه را باز کنید.
- Full clinical management advice
- Additional notes
- Evidence detail
- Interaction checker for a whole prescription
Pro+ را ۱۴ روز رایگان در وب امتحان کنید. بدون نیاز به کارت.
تداخلات دیگر Cefuroxime
تداخلات دیگر Amikacin
پرسش‌های متداول
Can I take Amikacin with Cefuroxime?
MediHelp rates the interaction as moderate. Amikacin and Cefuroxime can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Cefuroxime given with amikacin may increase the risk of kidney injury, especially in older, dehydrated or renally impaired patients. Amikacin is the principal nephrotoxic and ototoxic agent, and the combination is often used on purpose in serious infections.
How serious is the interaction between Amikacin and Cefuroxime?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor serum creatinine and amikacin levels, keep the patient hydrated and limit the aminoglycoside duration. Adjust the doses for renal function.
What other medicines interact with Cefuroxime?
MediHelp also lists interactions of Cefuroxime with, for example, Aluminum hydroxide, Bcg vaccine live, Calcium carbonate. The full list is on the Cefuroxime page.
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