تداخل‌های دارویی
Anastrozole + Desogestrel-ethinyl estradiol
شدت: شدید
Anastrozole and Desogestrel-ethinyl estradiol: major interaction.
آخرین به‌روزرسانی
ویژه کادر درمان — فقط جهت مرجع. این صفحه خلاصه‌ای کوتاه است، توصیه پزشکی نیست و جایگزین بروشور رسمی یا قضاوت بالینی نمی‌شود. پیش از تجویز یا تحویل دارو همیشه بررسی کنید.
محتوای بالینی این صفحه فقط به زبان انگلیسی موجود است.
خلاصه
Anastrozole works by lowering estrogen levels, and exogenous estrogen such as ethinyl estradiol opposes this effect. The combination undermines the therapeutic aim in hormone-receptor-positive breast cancer, and anastrozole is not intended for use in premenopausal women who might need contraception.
معنای این تداخل به زبان ساده
Anastrozole and Desogestrel-ethinyl estradiol can interact in a way that may be serious. Using them together is sometimes necessary, but it needs a deliberate decision by the prescriber, a plan for monitoring, and clear advice on the warning signs to watch for.
Anastrozole belongs to Oncology; Desogestrel-ethinyl estradiol belongs to Endocrine.
چرا رخ می‌دهد
Pharmacodynamic antagonism: exogenous estrogen counteracts aromatase inhibition-induced estrogen suppression.
اقدام لازم
Avoid combined estrogen-containing products in patients taking anastrozole; use a non-hormonal contraceptive if contraception is needed.
از داروساز چه بپرسید
- Does the benefit of taking both outweigh the risk in my case?
- Do I need any blood test, ECG or other check while on both?
- What early warning signs should I watch for, and what should I do if they appear?
ویژه اعضای Pro+
باز کردن کل صفحه
یک حساب بسازید و دوره آزمایشی Pro+ را شروع کنید تا توصیه‌های کامل مدیریت Anastrozole و Desogestrel-ethinyl estradiol، یادداشت‌های تکمیلی، جزئیات شواهد و بررسی‌کننده تداخل برای کل نسخه را باز کنید.
- Full clinical management advice
- Additional notes
- Evidence detail
- Interaction checker for a whole prescription
Pro+ را ۱۴ روز رایگان در وب امتحان کنید. بدون نیاز به کارت.
تداخلات دیگر Desogestrel-ethinyl estradiol
تداخلات دیگر Anastrozole
پرسش‌های متداول
Can I take Anastrozole with Desogestrel-ethinyl estradiol?
MediHelp rates the interaction as major. Anastrozole and Desogestrel-ethinyl estradiol can interact in a way that may be serious. Using them together is sometimes necessary, but it needs a deliberate decision by the prescriber, a plan for monitoring, and clear advice on the warning signs to watch for. Anastrozole works by lowering estrogen levels, and exogenous estrogen such as ethinyl estradiol opposes this effect. The combination undermines the therapeutic aim in hormone-receptor-positive breast cancer, and anastrozole is not intended for use in premenopausal women who might need contraception.
How serious is the interaction between Anastrozole and Desogestrel-ethinyl estradiol?
MediHelp rates it major, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Avoid combined estrogen-containing products in patients taking anastrozole; use a non-hormonal contraceptive if contraception is needed.
What other medicines interact with Desogestrel-ethinyl estradiol?
MediHelp also lists interactions of Desogestrel-ethinyl estradiol with, for example, Fezolinetant, Aminocaproic acid, Amobarbital. The full list is on the Desogestrel-ethinyl estradiol page.
تک‌نگاری کامل، دوزاژ و بررسی تداخل دارویی در برنامه MediHelp
مرجع کامل را باز کنید، تداخل چند دارو را بررسی کنید و از ابزارهای دوز در برنامه MediHelp استفاده کنید.
