تداخل‌های دارویی
Anti-thymocyte + Tofacitinib
شدت: شدید
Anti-thymocyte and Tofacitinib: major interaction.
آخرین به‌روزرسانی
ویژه کادر درمان — فقط جهت مرجع. این صفحه خلاصه‌ای کوتاه است، توصیه پزشکی نیست و جایگزین بروشور رسمی یا قضاوت بالینی نمی‌شود. پیش از تجویز یا تحویل دارو همیشه بررسی کنید.
محتوای بالینی این صفحه فقط به زبان انگلیسی موجود است.
خلاصه
Tofacitinib is a Janus kinase inhibitor that impairs cytokine signalling, and anti-thymocyte globulin depletes T cells. Combined use markedly increases the risk of serious opportunistic and other infections.
معنای این تداخل به زبان ساده
Anti-thymocyte and Tofacitinib can interact in a way that may be serious. Using them together is sometimes necessary, but it needs a deliberate decision by the prescriber, a plan for monitoring, and clear advice on the warning signs to watch for.
Anti-thymocyte belongs to Miscellaneous; Tofacitinib belongs to Musculoskeletal.
چرا رخ می‌دهد
Additive immunosuppression through T-cell depletion and JAK inhibition.
اقدام لازم
Avoid combining where possible; the label advises against use of tofacitinib with potent immunosuppressants. If combined, monitor closely for infection and use appropriate prophylaxis.
از داروساز چه بپرسید
- Does the benefit of taking both outweigh the risk in my case?
- Do I need any blood test, ECG or other check while on both?
- What early warning signs should I watch for, and what should I do if they appear?
ویژه اعضای Pro+
باز کردن کل صفحه
یک حساب بسازید و دوره آزمایشی Pro+ را شروع کنید تا توصیه‌های کامل مدیریت Anti-thymocyte و Tofacitinib، یادداشت‌های تکمیلی، جزئیات شواهد و بررسی‌کننده تداخل برای کل نسخه را باز کنید.
- Full clinical management advice
- Additional notes
- Evidence detail
- Interaction checker for a whole prescription
Pro+ را ۱۴ روز رایگان در وب امتحان کنید. بدون نیاز به کارت.
تداخلات دیگر Anti-thymocyte
- Anti-thymocyte + Bcg vaccine live منع مصرف
- Anti-thymocyte + Influenza virus vaccine quadrivalent intranasal منع مصرف
- Anti-thymocyte + Measles mumps and rubella vaccine live منع مصرف
- Anti-thymocyte + Measles mumps rubella and varicella vaccine live منع مصرف
- Anti-thymocyte + Measles vaccine منع مصرف
- Anti-thymocyte + Rotavirus oral vaccine live منع مصرف
تداخلات دیگر Tofacitinib
پرسش‌های متداول
Can I take Anti-thymocyte with Tofacitinib?
MediHelp rates the interaction as major. Anti-thymocyte and Tofacitinib can interact in a way that may be serious. Using them together is sometimes necessary, but it needs a deliberate decision by the prescriber, a plan for monitoring, and clear advice on the warning signs to watch for. Tofacitinib is a Janus kinase inhibitor that impairs cytokine signalling, and anti-thymocyte globulin depletes T cells. Combined use markedly increases the risk of serious opportunistic and other infections.
How serious is the interaction between Anti-thymocyte and Tofacitinib?
MediHelp rates it major, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Avoid combining where possible; the label advises against use of tofacitinib with potent immunosuppressants. If combined, monitor closely for infection and use appropriate prophylaxis.
What other medicines interact with Anti-thymocyte?
MediHelp also lists interactions of Anti-thymocyte with, for example, Bcg vaccine live, Influenza virus vaccine quadrivalent intranasal, Measles mumps and rubella vaccine live. The full list is on the Anti-thymocyte page.
تک‌نگاری کامل، دوزاژ و بررسی تداخل دارویی در برنامه MediHelp
مرجع کامل را باز کنید، تداخل چند دارو را بررسی کنید و از ابزارهای دوز در برنامه MediHelp استفاده کنید.
