تداخل‌های دارویی
Aripiprazole + Sufentanil
شدت: شدید
Aripiprazole and Sufentanil: major interaction.
آخرین به‌روزرسانی منابع: UK SmPC
ویژه کادر درمان — فقط جهت مرجع. این صفحه خلاصه‌ای کوتاه است، توصیه پزشکی نیست و جایگزین بروشور رسمی یا قضاوت بالینی نمی‌شود. پیش از تجویز یا تحویل دارو همیشه بررسی کنید.
محتوای بالینی این صفحه فقط به زبان انگلیسی موجود است.
خلاصه
Opioids combined with other CNS depressants increase the risk of profound sedation, respiratory depression and hypotension. Aripiprazole has milder sedative effects but contributes to additive depression.
معنای این تداخل به زبان ساده
Aripiprazole and Sufentanil can interact in a way that may be serious. Using them together is sometimes necessary, but it needs a deliberate decision by the prescriber, a plan for monitoring, and clear advice on the warning signs to watch for.
Aripiprazole belongs to Central Nervous System; Sufentanil belongs to Musculoskeletal.
چرا رخ می‌دهد
Additive CNS and respiratory depression, with additive hypotensive effects.
اقدام لازم
Use the lowest effective sufentanil dose and monitor respiratory rate, sedation and blood pressure. Ensure appropriate monitoring and resuscitation capability in procedural settings.
از داروساز چه بپرسید
- Does the benefit of taking both outweigh the risk in my case?
- Do I need any blood test, ECG or other check while on both?
- What early warning signs should I watch for, and what should I do if they appear?
ویژه اعضای Pro+
باز کردن کل صفحه
یک حساب بسازید و دوره آزمایشی Pro+ را شروع کنید تا توصیه‌های کامل مدیریت Aripiprazole و Sufentanil، یادداشت‌های تکمیلی، جزئیات شواهد و بررسی‌کننده تداخل برای کل نسخه را باز کنید.
- Full clinical management advice
- Additional notes
- Evidence detail
- Interaction checker for a whole prescription
Pro+ را ۷ روز رایگان در وب امتحان کنید. بدون نیاز به کارت.
منابع
- Abilify 1 mg/mL Oral Solution - SmPC sections 4.3/4.5 (class statement: other CNS medicinal products with overlapping adverse reactions such as sedation; "caution should be used when aripiprazole is administered in combination with alcohol or other CNS medicinal products with overlapping adverse re… — electronic medicines compendium (UK SmPC)
تداخلات دیگر Aripiprazole
تداخلات دیگر Sufentanil
پرسش‌های متداول
Can I take Aripiprazole with Sufentanil?
MediHelp rates the interaction as major. Aripiprazole and Sufentanil can interact in a way that may be serious. Using them together is sometimes necessary, but it needs a deliberate decision by the prescriber, a plan for monitoring, and clear advice on the warning signs to watch for. Opioids combined with other CNS depressants increase the risk of profound sedation, respiratory depression and hypotension. Aripiprazole has milder sedative effects but contributes to additive depression.
How serious is the interaction between Aripiprazole and Sufentanil?
MediHelp rates it major, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Use the lowest effective sufentanil dose and monitor respiratory rate, sedation and blood pressure. Ensure appropriate monitoring and resuscitation capability in procedural settings.
What other medicines interact with Aripiprazole?
MediHelp also lists interactions of Aripiprazole with, for example, Pimozide, Thioridazine, Amisulpride. The full list is on the Aripiprazole page.
تک‌نگاری کامل، دوزاژ و بررسی تداخل دارویی در برنامه MediHelp
مرجع کامل را باز کنید، تداخل چند دارو را بررسی کنید و از ابزارهای دوز در برنامه MediHelp استفاده کنید.
