تداخل‌های دارویی
Atenolol + Bismuth subsalicylate
شدت: متوسط
Atenolol and Bismuth subsalicylate: moderate interaction.
آخرین به‌روزرسانی
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خلاصه
Bismuth subsalicylate releases salicylate, which may inhibit renal prostaglandin synthesis, causing sodium and water retention and blunting the antihypertensive effect of beta-blockers. The effect is chiefly seen with regular high-dose salicylate use and is generally modest with short courses.
معنای این تداخل به زبان ساده
Atenolol and Bismuth subsalicylate can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Atenolol belongs to Cardiovascular; Bismuth subsalicylate belongs to Gastrointestinal Tract.
چرا رخ می‌دهد
Salicylate inhibits prostaglandin synthesis, causing sodium and fluid retention that opposes the antihypertensive effect.
اقدام لازم
Limit bismuth subsalicylate to short courses and monitor blood pressure if used repeatedly. Use an alternative antidiarrheal or antacid for prolonged treatment.
از داروساز چه بپرسید
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
ویژه اعضای Pro+
باز کردن کل صفحه
یک حساب بسازید و دوره آزمایشی Pro+ را شروع کنید تا توصیه‌های کامل مدیریت Atenolol و Bismuth subsalicylate، یادداشت‌های تکمیلی، جزئیات شواهد و بررسی‌کننده تداخل برای کل نسخه را باز کنید.
- Full clinical management advice
- Additional notes
- Evidence detail
- Interaction checker for a whole prescription
Pro+ را ۱۴ روز رایگان در وب امتحان کنید. بدون نیاز به کارت.
تداخلات دیگر Bismuth subsalicylate
تداخلات دیگر Atenolol
پرسش‌های متداول
Can I take Atenolol with Bismuth subsalicylate?
MediHelp rates the interaction as moderate. Atenolol and Bismuth subsalicylate can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Bismuth subsalicylate releases salicylate, which may inhibit renal prostaglandin synthesis, causing sodium and water retention and blunting the antihypertensive effect of beta-blockers. The effect is chiefly seen with regular high-dose salicylate use and is generally modest with short courses.
How serious is the interaction between Atenolol and Bismuth subsalicylate?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Limit bismuth subsalicylate to short courses and monitor blood pressure if used repeatedly. Use an alternative antidiarrheal or antacid for prolonged treatment.
What other medicines interact with Bismuth subsalicylate?
MediHelp also lists interactions of Bismuth subsalicylate with, for example, Dichlorphenamide, Warfarin, Acetylsalicylic acid. The full list is on the Bismuth subsalicylate page.
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