تداخل‌های دارویی
Atracurium + Benzhydrocodone / acetaminophen
شدت: شدید
Atracurium and Benzhydrocodone / acetaminophen: major interaction.
آخرین به‌روزرسانی
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محتوای بالینی این صفحه فقط به زبان انگلیسی موجود است.
خلاصه
Opioids combined with neuromuscular blockers can add to respiratory compromise, and the opioid's sedation may mask inadequate ventilation. Atracurium is used only with ventilatory support, so the practical risk arises when residual blockade overlaps with opioid-induced respiratory depression.
معنای این تداخل به زبان ساده
Atracurium and Benzhydrocodone / acetaminophen can interact in a way that may be serious. Using them together is sometimes necessary, but it needs a deliberate decision by the prescriber, a plan for monitoring, and clear advice on the warning signs to watch for.
چرا رخ می‌دهد
Additive respiratory depression: central opioid-mediated depression plus peripheral neuromuscular blockade.
اقدام لازم
Use only with controlled ventilation and monitor neuromuscular blockade and respiratory status until full recovery. Use the lowest effective opioid dose and duration.
از داروساز چه بپرسید
- Does the benefit of taking both outweigh the risk in my case?
- Do I need any blood test, ECG or other check while on both?
- What early warning signs should I watch for, and what should I do if they appear?
ویژه اعضای Pro+
باز کردن کل صفحه
یک حساب بسازید و دوره آزمایشی Pro+ را شروع کنید تا توصیه‌های کامل مدیریت Atracurium و Benzhydrocodone / acetaminophen، یادداشت‌های تکمیلی، جزئیات شواهد و بررسی‌کننده تداخل برای کل نسخه را باز کنید.
- Full clinical management advice
- Additional notes
- Evidence detail
- Interaction checker for a whole prescription
Pro+ را ۱۴ روز رایگان در وب امتحان کنید. بدون نیاز به کارت.
تداخلات دیگر Atracurium
پرسش‌های متداول
Can I take Atracurium with Benzhydrocodone / acetaminophen?
MediHelp rates the interaction as major. Atracurium and Benzhydrocodone / acetaminophen can interact in a way that may be serious. Using them together is sometimes necessary, but it needs a deliberate decision by the prescriber, a plan for monitoring, and clear advice on the warning signs to watch for. Opioids combined with neuromuscular blockers can add to respiratory compromise, and the opioid's sedation may mask inadequate ventilation. Atracurium is used only with ventilatory support, so the practical risk arises when residual blockade overlaps with opioid-induced respiratory depression.
How serious is the interaction between Atracurium and Benzhydrocodone / acetaminophen?
MediHelp rates it major, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Use only with controlled ventilation and monitor neuromuscular blockade and respiratory status until full recovery. Use the lowest effective opioid dose and duration.
What other medicines interact with Atracurium?
MediHelp also lists interactions of Atracurium with, for example, Amikacin, Bacitracin-neomycin-polymyxin, Capreomycin. The full list is on the Atracurium page.
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