تداخل‌های دارویی
Axicabtagene ciloleucel + Basiliximab
شدت: شدید
Axicabtagene ciloleucel and Basiliximab: major interaction.
آخرین به‌روزرسانی
ویژه کادر درمان — فقط جهت مرجع. این صفحه خلاصه‌ای کوتاه است، توصیه پزشکی نیست و جایگزین بروشور رسمی یا قضاوت بالینی نمی‌شود. پیش از تجویز یا تحویل دارو همیشه بررسی کنید.
محتوای بالینی این صفحه فقط به زبان انگلیسی موجود است.
خلاصه
Basiliximab blocks IL-2 receptor on activated T cells, which could impair expansion and activity of CAR T cells and weaken efficacy. It also adds to infection risk after lymphodepletion.
معنای این تداخل به زبان ساده
Axicabtagene ciloleucel and Basiliximab can interact in a way that may be serious. Using them together is sometimes necessary, but it needs a deliberate decision by the prescriber, a plan for monitoring, and clear advice on the warning signs to watch for.
Axicabtagene ciloleucel belongs to Oncology; Basiliximab belongs to Miscellaneous.
چرا رخ می‌دهد
Pharmacodynamic antagonism of CAR T-cell proliferation through IL-2 receptor blockade and additive immunosuppression.
اقدام لازم
Avoid basiliximab around CAR T infusion unless clearly needed; coordinate with the treating oncology team and monitor for infection.
از داروساز چه بپرسید
- Does the benefit of taking both outweigh the risk in my case?
- Do I need any blood test, ECG or other check while on both?
- What early warning signs should I watch for, and what should I do if they appear?
ویژه اعضای Pro+
باز کردن کل صفحه
یک حساب بسازید و دوره آزمایشی Pro+ را شروع کنید تا توصیه‌های کامل مدیریت Axicabtagene ciloleucel و Basiliximab، یادداشت‌های تکمیلی، جزئیات شواهد و بررسی‌کننده تداخل برای کل نسخه را باز کنید.
- Full clinical management advice
- Additional notes
- Evidence detail
- Interaction checker for a whole prescription
Pro+ را ۱۴ روز رایگان در وب امتحان کنید. بدون نیاز به کارت.
تداخلات دیگر Basiliximab
- Basiliximab + Bcg vaccine live منع مصرف
- Basiliximab + Influenza virus vaccine quadrivalent intranasal منع مصرف
- Basiliximab + Measles mumps and rubella vaccine منع مصرف
- Basiliximab + Measles mumps and rubella vaccine live منع مصرف
- Basiliximab + Measles mumps rubella and varicella vaccine live منع مصرف
- Basiliximab + Measles vaccine منع مصرف
تداخلات دیگر Axicabtagene ciloleucel
پرسش‌های متداول
Can I take Axicabtagene ciloleucel with Basiliximab?
MediHelp rates the interaction as major. Axicabtagene ciloleucel and Basiliximab can interact in a way that may be serious. Using them together is sometimes necessary, but it needs a deliberate decision by the prescriber, a plan for monitoring, and clear advice on the warning signs to watch for. Basiliximab blocks IL-2 receptor on activated T cells, which could impair expansion and activity of CAR T cells and weaken efficacy. It also adds to infection risk after lymphodepletion.
How serious is the interaction between Axicabtagene ciloleucel and Basiliximab?
MediHelp rates it major, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Avoid basiliximab around CAR T infusion unless clearly needed; coordinate with the treating oncology team and monitor for infection.
What other medicines interact with Basiliximab?
MediHelp also lists interactions of Basiliximab with, for example, Bcg vaccine live, Influenza virus vaccine quadrivalent intranasal, Measles mumps and rubella vaccine. The full list is on the Basiliximab page.
تک‌نگاری کامل، دوزاژ و بررسی تداخل دارویی در برنامه MediHelp
مرجع کامل را باز کنید، تداخل چند دارو را بررسی کنید و از ابزارهای دوز در برنامه MediHelp استفاده کنید.
