تداخل‌های دارویی
Basiliximab + Lisocabtagene maraleucel
شدت: شدید
Basiliximab and Lisocabtagene maraleucel: major interaction.
آخرین به‌روزرسانی
ویژه کادر درمان — فقط جهت مرجع. این صفحه خلاصه‌ای کوتاه است، توصیه پزشکی نیست و جایگزین بروشور رسمی یا قضاوت بالینی نمی‌شود. پیش از تجویز یا تحویل دارو همیشه بررسی کنید.
محتوای بالینی این صفحه فقط به زبان انگلیسی موجود است.
خلاصه
Lisocabtagene maraleucel is a CAR T-cell therapy that depends on functional T-cell expansion, while basiliximab inhibits activated T cells through IL-2 receptor blockade. Combined use may reduce CAR T-cell efficacy and adds to infection risk in an already immunocompromised patient.
معنای این تداخل به زبان ساده
Basiliximab and Lisocabtagene maraleucel can interact in a way that may be serious. Using them together is sometimes necessary, but it needs a deliberate decision by the prescriber, a plan for monitoring, and clear advice on the warning signs to watch for.
Basiliximab belongs to Miscellaneous; Lisocabtagene maraleucel belongs to Oncology.
چرا رخ می‌دهد
Basiliximab blocks CD25 on activated T cells, which may impair CAR T-cell proliferation and persistence, with additive immunosuppression.
اقدام لازم
Avoid basiliximab around CAR T-cell infusion unless essential, and choose alternative approaches where possible. If used, monitor closely for infection and for loss of CAR T-cell response.
از داروساز چه بپرسید
- Does the benefit of taking both outweigh the risk in my case?
- Do I need any blood test, ECG or other check while on both?
- What early warning signs should I watch for, and what should I do if they appear?
ویژه اعضای Pro+
باز کردن کل صفحه
یک حساب بسازید و دوره آزمایشی Pro+ را شروع کنید تا توصیه‌های کامل مدیریت Basiliximab و Lisocabtagene maraleucel، یادداشت‌های تکمیلی، جزئیات شواهد و بررسی‌کننده تداخل برای کل نسخه را باز کنید.
- Full clinical management advice
- Additional notes
- Evidence detail
- Interaction checker for a whole prescription
Pro+ را ۱۴ روز رایگان در وب امتحان کنید. بدون نیاز به کارت.
تداخلات دیگر Basiliximab
- Basiliximab + Bcg vaccine live منع مصرف
- Basiliximab + Influenza virus vaccine quadrivalent intranasal منع مصرف
- Basiliximab + Measles mumps and rubella vaccine منع مصرف
- Basiliximab + Measles mumps and rubella vaccine live منع مصرف
- Basiliximab + Measles mumps rubella and varicella vaccine live منع مصرف
- Basiliximab + Measles vaccine منع مصرف
تداخلات دیگر Lisocabtagene maraleucel
پرسش‌های متداول
Can I take Basiliximab with Lisocabtagene maraleucel?
MediHelp rates the interaction as major. Basiliximab and Lisocabtagene maraleucel can interact in a way that may be serious. Using them together is sometimes necessary, but it needs a deliberate decision by the prescriber, a plan for monitoring, and clear advice on the warning signs to watch for. Lisocabtagene maraleucel is a CAR T-cell therapy that depends on functional T-cell expansion, while basiliximab inhibits activated T cells through IL-2 receptor blockade. Combined use may reduce CAR T-cell efficacy and adds to infection risk in an already immunocompromised patient.
How serious is the interaction between Basiliximab and Lisocabtagene maraleucel?
MediHelp rates it major, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Avoid basiliximab around CAR T-cell infusion unless essential, and choose alternative approaches where possible. If used, monitor closely for infection and for loss of CAR T-cell response.
What other medicines interact with Basiliximab?
MediHelp also lists interactions of Basiliximab with, for example, Bcg vaccine live, Influenza virus vaccine quadrivalent intranasal, Measles mumps and rubella vaccine. The full list is on the Basiliximab page.
تک‌نگاری کامل، دوزاژ و بررسی تداخل دارویی در برنامه MediHelp
مرجع کامل را باز کنید، تداخل چند دارو را بررسی کنید و از ابزارهای دوز در برنامه MediHelp استفاده کنید.
