تداخلهای دارویی
Benzphetamine + Selegiline
شدت: منع مصرف
Benzphetamine and Selegiline: contraindicated interaction.
آخرین بهروزرسانی
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محتوای بالینی این صفحه فقط به زبان انگلیسی موجود است.
خلاصه
Selegiline, particularly in the transdermal form that provides non-selective MAO inhibition, can greatly amplify the sympathomimetic effects of benzphetamine. This may precipitate a hypertensive crisis with severe headache, arrhythmia or intracranial haemorrhage.
معنای این تداخل به زبان ساده
Benzphetamine and Selegiline are not normally used together. Taking them at the same time is expected to cause harm or make one of them unsafe, so a different medicine is usually chosen for one of the two.
چرا رخ میدهد
MAO inhibition allows accumulation of norepinephrine and other monoamines, and benzphetamine adds indirect sympathomimetic release, producing additive pressor effects.
اقدام لازم
Do not co-administer; benzphetamine labeling contraindicates use during or within 14 days of an MAO inhibitor. Choose a non-sympathomimetic weight management approach.
از داروساز چه بپرسید
- Is there an alternative to one of these two medicines for me?
- If both are essential, who is monitoring me and how often?
- Which symptoms mean I should stop and seek help straight away?
ویژه اعضای Pro+
باز کردن کل صفحه
یک حساب بسازید و دوره آزمایشی Pro+ را شروع کنید تا توصیههای کامل مدیریت Benzphetamine و Selegiline، یادداشتهای تکمیلی، جزئیات شواهد و بررسیکننده تداخل برای کل نسخه را باز کنید.
- Full clinical management advice
- Additional notes
- Evidence detail
- Interaction checker for a whole prescription
Pro+ را ۱۴ روز رایگان در وب امتحان کنید. بدون نیاز به کارت.
تداخلات دیگر Selegiline
- Amitriptyline + Selegiline منع مصرف
- Amoxapine + Selegiline منع مصرف
- Atomoxetine + Selegiline منع مصرف
- Brimonidine + Selegiline منع مصرف
- Buprenorphine long-acting + Selegiline منع مصرف
- Bupropion-naltrexone + Selegiline منع مصرف
پرسشهای متداول
Can I take Benzphetamine with Selegiline?
MediHelp rates the interaction as contraindicated. Benzphetamine and Selegiline are not normally used together. Taking them at the same time is expected to cause harm or make one of them unsafe, so a different medicine is usually chosen for one of the two. Selegiline, particularly in the transdermal form that provides non-selective MAO inhibition, can greatly amplify the sympathomimetic effects of benzphetamine. This may precipitate a hypertensive crisis with severe headache, arrhythmia or intracranial haemorrhage.
How serious is the interaction between Benzphetamine and Selegiline?
MediHelp rates it contraindicated, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Do not co-administer; benzphetamine labeling contraindicates use during or within 14 days of an MAO inhibitor. Choose a non-sympathomimetic weight management approach.
What other medicines interact with Selegiline?
MediHelp also lists interactions of Selegiline with, for example, Amitriptyline, Amoxapine, Atomoxetine. The full list is on the Selegiline page.
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مرجع کامل را باز کنید، تداخل چند دارو را بررسی کنید و از ابزارهای دوز در برنامه MediHelp استفاده کنید.