تداخلهای دارویی
Brexucabtagene autoleucel + Capecitabine
شدت: شدید
Brexucabtagene autoleucel and Capecitabine: major interaction.
آخرین بهروزرسانی
ویژه کادر درمان — فقط جهت مرجع. این صفحه خلاصهای کوتاه است، توصیه پزشکی نیست و جایگزین بروشور رسمی یا قضاوت بالینی نمیشود. پیش از تجویز یا تحویل دارو همیشه بررسی کنید.
محتوای بالینی این صفحه فقط به زبان انگلیسی موجود است.
خلاصه
Capecitabine can cause lymphopenia and myelosuppression, which may impair collection, expansion and persistence of CAR T cells. It also adds to the infection risk after CAR T therapy.
معنای این تداخل به زبان ساده
Brexucabtagene autoleucel and Capecitabine can interact in a way that may be serious. Using them together is sometimes necessary, but it needs a deliberate decision by the prescriber, a plan for monitoring, and clear advice on the warning signs to watch for.
Brexucabtagene autoleucel belongs to Oncology; Capecitabine belongs to Oncology.
چرا رخ میدهد
Cytotoxic myelosuppression and lymphodepletion may compromise CAR T-cell function and add to immunosuppression.
اقدام لازم
Avoid capecitabine in the window before leukapheresis and during CAR T recovery unless clearly needed. Coordinate timing with the CAR T team and monitor for infection and cytopenias.
از داروساز چه بپرسید
- Does the benefit of taking both outweigh the risk in my case?
- Do I need any blood test, ECG or other check while on both?
- What early warning signs should I watch for, and what should I do if they appear?
ویژه اعضای Pro+
باز کردن کل صفحه
یک حساب بسازید و دوره آزمایشی Pro+ را شروع کنید تا توصیههای کامل مدیریت Brexucabtagene autoleucel و Capecitabine، یادداشتهای تکمیلی، جزئیات شواهد و بررسیکننده تداخل برای کل نسخه را باز کنید.
- Full clinical management advice
- Additional notes
- Evidence detail
- Interaction checker for a whole prescription
Pro+ را ۱۴ روز رایگان در وب امتحان کنید. بدون نیاز به کارت.
تداخلات دیگر Capecitabine
تداخلات دیگر Brexucabtagene autoleucel
پرسشهای متداول
Can I take Brexucabtagene autoleucel with Capecitabine?
MediHelp rates the interaction as major. Brexucabtagene autoleucel and Capecitabine can interact in a way that may be serious. Using them together is sometimes necessary, but it needs a deliberate decision by the prescriber, a plan for monitoring, and clear advice on the warning signs to watch for. Capecitabine can cause lymphopenia and myelosuppression, which may impair collection, expansion and persistence of CAR T cells. It also adds to the infection risk after CAR T therapy.
How serious is the interaction between Brexucabtagene autoleucel and Capecitabine?
MediHelp rates it major, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Avoid capecitabine in the window before leukapheresis and during CAR T recovery unless clearly needed. Coordinate timing with the CAR T team and monitor for infection and cytopenias.
What other medicines interact with Capecitabine?
MediHelp also lists interactions of Capecitabine with, for example, Adenovirus types 4 and 7 live, Arsenic trioxide, Axicabtagene ciloleucel. The full list is on the Capecitabine page.
تکنگاری کامل، دوزاژ و بررسی تداخل دارویی در برنامه MediHelp
مرجع کامل را باز کنید، تداخل چند دارو را بررسی کنید و از ابزارهای دوز در برنامه MediHelp استفاده کنید.