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Cefixime + Sodium picosulfate / magnesium oxide / anhydrous citric acid

شدت: متوسط

Cefixime and Sodium picosulfate / magnesium oxide / anhydrous citric acid: moderate interaction.

آخرین به‌روزرسانی

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خلاصه

Sodium picosulfate is a prodrug that must be converted to its active form by colonic bacteria. Antibiotics that suppress gut flora may reduce this conversion and lead to a less effective bowel cleansing before colonoscopy.

معنای این تداخل به زبان ساده

Cefixime and Sodium picosulfate / magnesium oxide / anhydrous citric acid can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.

سطح شواهد: Moderate

چرا رخ می‌دهد

Antibiotic suppression of colonic bacteria reduces conversion of picosulfate to its active laxative metabolite.

اقدام لازم

If possible, avoid starting the antibiotic until after the bowel preparation has been completed. Assess the quality of bowel cleansing and be prepared to use an additional preparation if it is inadequate.

از داروساز چه بپرسید

  • Should I take them at different times of day?
  • Does the dose of either medicine need to change?
  • Is there anything I should avoid, such as alcohol or certain foods, while on both?

Bring a full list of your medicines, including over-the-counter products, supplements and herbal remedies, to every pharmacy visit.

ویژه اعضای Pro+

باز کردن کل صفحه

یک حساب بسازید و دوره آزمایشی Pro+ را شروع کنید تا توصیه‌های کامل مدیریت Cefixime و Sodium picosulfate / magnesium oxide / anhydrous citric acid، یادداشت‌های تکمیلی، جزئیات شواهد و بررسی‌کننده تداخل برای کل نسخه را باز کنید.

  • Full clinical management advice
  • Additional notes
  • Evidence detail
  • Interaction checker for a whole prescription

Pro+ را ۱۴ روز رایگان در وب امتحان کنید. بدون نیاز به کارت.

پرسش‌های متداول

Can I take Cefixime with Sodium picosulfate / magnesium oxide / anhydrous citric acid?

MediHelp rates the interaction as moderate. Cefixime and Sodium picosulfate / magnesium oxide / anhydrous citric acid can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Sodium picosulfate is a prodrug that must be converted to its active form by colonic bacteria. Antibiotics that suppress gut flora may reduce this conversion and lead to a less effective bowel cleansing before colonoscopy.

How serious is the interaction between Cefixime and Sodium picosulfate / magnesium oxide / anhydrous citric acid?

MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: If possible, avoid starting the antibiotic until after the bowel preparation has been completed. Assess the quality of bowel cleansing and be prepared to use an additional preparation if it is inadequate.

What other medicines interact with Cefixime?

MediHelp also lists interactions of Cefixime with, for example, Typhoid vaccine live, Cholera vaccine, Kanamycin. The full list is on the Cefixime page.

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