تداخل‌های دارویی
Cefoxitin + Kanamycin
شدت: متوسط
Cefoxitin and Kanamycin: moderate interaction.
آخرین به‌روزرسانی
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محتوای بالینی این صفحه فقط به زبان انگلیسی موجود است.
خلاصه
Giving a cephalosporin with an aminoglycoside may add to kidney injury, and aminoglycosides can also damage the inner ear. The risk is greatest in patients with existing renal impairment, older adults or those receiving prolonged courses.
معنای این تداخل به زبان ساده
Cefoxitin and Kanamycin can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
چرا رخ می‌دهد
Additive nephrotoxic potential, with aminoglycoside-related tubular injury and ototoxicity possibly aggravated by reduced renal clearance.
اقدام لازم
Monitor serum creatinine and urine output during combined therapy and check kanamycin levels where available. Adjust the aminoglycoside dose to renal function and report any hearing or balance symptoms promptly.
از داروساز چه بپرسید
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
ویژه اعضای Pro+
باز کردن کل صفحه
یک حساب بسازید و دوره آزمایشی Pro+ را شروع کنید تا توصیه‌های کامل مدیریت Cefoxitin و Kanamycin، یادداشت‌های تکمیلی، جزئیات شواهد و بررسی‌کننده تداخل برای کل نسخه را باز کنید.
- Full clinical management advice
- Additional notes
- Evidence detail
- Interaction checker for a whole prescription
Pro+ را ۷ روز رایگان در وب امتحان کنید. بدون نیاز به کارت.
تداخلات دیگر Cefoxitin
پرسش‌های متداول
Can I take Cefoxitin with Kanamycin?
MediHelp rates the interaction as moderate. Cefoxitin and Kanamycin can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Giving a cephalosporin with an aminoglycoside may add to kidney injury, and aminoglycosides can also damage the inner ear. The risk is greatest in patients with existing renal impairment, older adults or those receiving prolonged courses.
How serious is the interaction between Cefoxitin and Kanamycin?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor serum creatinine and urine output during combined therapy and check kanamycin levels where available. Adjust the aminoglycoside dose to renal function and report any hearing or balance symptoms promptly.
What other medicines interact with Cefoxitin?
MediHelp also lists interactions of Cefoxitin with, for example, Amikacin, Aztreonam, Bcg vaccine live. The full list is on the Cefoxitin page.
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