تداخل‌های دارویی
Ceftriaxone + Ringer's solution
شدت: منع مصرف
Ceftriaxone and Ringer's solution: contraindicated interaction.
آخرین به‌روزرسانی منابع: US FDA label
ویژه کادر درمان — فقط جهت مرجع. این صفحه خلاصه‌ای کوتاه است، توصیه پزشکی نیست و جایگزین بروشور رسمی یا قضاوت بالینی نمی‌شود. پیش از تجویز یا تحویل دارو همیشه بررسی کنید.
محتوای بالینی این صفحه فقط به زبان انگلیسی موجود است.
خلاصه
Ceftriaxone can form an insoluble ceftriaxone-calcium precipitate when mixed with calcium-containing solutions such as Ringer's or lactated Ringer's. Fatal cases of crystalline deposits in the lungs and kidneys have occurred in neonates given ceftriaxone and calcium-containing intravenous fluids. In neonates the combination is contraindicated, and in older patients it must not be mixed or co-infused in the same line.
معنای این تداخل به زبان ساده
Ceftriaxone and Ringer's solution are not normally used together. Taking them at the same time is expected to cause harm or make one of them unsafe, so a different medicine is usually chosen for one of the two.
چرا رخ می‌دهد
Ceftriaxone binds calcium to form poorly soluble ceftriaxone-calcium salt, which precipitates in IV lines and in vivo.
اقدام لازم
Do not give ceftriaxone to neonates (up to 28 days) who need or are expected to need calcium-containing IV solutions, including Ringer's.
از داروساز چه بپرسید
- Is there an alternative to one of these two medicines for me?
- If both are essential, who is monitoring me and how often?
- Which symptoms mean I should stop and seek help straight away?
ویژه اعضای Pro+
باز کردن کل صفحه
یک حساب بسازید و دوره آزمایشی Pro+ را شروع کنید تا توصیه‌های کامل مدیریت Ceftriaxone و Ringer's solution، یادداشت‌های تکمیلی، جزئیات شواهد و بررسی‌کننده تداخل برای کل نسخه را باز کنید.
- Full clinical management advice
- Additional notes
- Evidence detail
- Interaction checker for a whole prescription
Pro+ را ۱۴ روز رایگان در وب امتحان کنید. بدون نیاز به کارت.
منابع
- Rocephin (ceftriaxone) Prescribing Information - Contraindications and Warnings: Interaction with calcium-containing products — FDA Label
- Ceftriaxone Summary of Product Characteristics - Contraindications and Interactions with calcium — EMA SmPC
تداخلات دیگر Ceftriaxone
- Calcium chloride + Ceftriaxone منع مصرف
- Calcium gluconate + Ceftriaxone منع مصرف
- Calcium + Ceftriaxone منع مصرف
- Ceftriaxone + Lactated ringer's منع مصرف
- Calcium acetate + Ceftriaxone شدید
- Ceftriaxone + Lactated Ringer's solution شدید
پرسش‌های متداول
Can I take Ceftriaxone with Ringer's solution?
MediHelp rates the interaction as contraindicated. Ceftriaxone and Ringer's solution are not normally used together. Taking them at the same time is expected to cause harm or make one of them unsafe, so a different medicine is usually chosen for one of the two. Ceftriaxone can form an insoluble ceftriaxone-calcium precipitate when mixed with calcium-containing solutions such as Ringer's or lactated Ringer's. Fatal cases of crystalline deposits in the lungs and kidneys have occurred in neonates given ceftriaxone and calcium-containing intravenous fluids. In neonates the combination is contraindicated, and in older patients it must not be mixed or co-infused in the same line.
How serious is the interaction between Ceftriaxone and Ringer's solution?
MediHelp rates it contraindicated, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Do not give ceftriaxone to neonates (up to 28 days) who need or are expected to need calcium-containing IV solutions, including Ringer's.
What other medicines interact with Ceftriaxone?
MediHelp also lists interactions of Ceftriaxone with, for example, Calcium chloride, Calcium gluconate, Calcium. The full list is on the Ceftriaxone page.
تک‌نگاری کامل، دوزاژ و بررسی تداخل دارویی در برنامه MediHelp
مرجع کامل را باز کنید، تداخل چند دارو را بررسی کنید و از ابزارهای دوز در برنامه MediHelp استفاده کنید.
