تداخل‌های دارویی
Cholestyramine + Mycophenolate mofetil
شدت: شدید
Cholestyramine and Mycophenolate mofetil: major interaction.
آخرین به‌روزرسانی
ویژه کادر درمان — فقط جهت مرجع. این صفحه خلاصه‌ای کوتاه است، توصیه پزشکی نیست و جایگزین بروشور رسمی یا قضاوت بالینی نمی‌شود. پیش از تجویز یا تحویل دارو همیشه بررسی کنید.
محتوای بالینی این صفحه فقط به زبان انگلیسی موجود است.
خلاصه
Cholestyramine binds mycophenolic acid in the gut and interrupts its enterohepatic circulation, reducing exposure by about 40 percent. Loss of immunosuppression raises the risk of rejection.
معنای این تداخل به زبان ساده
Cholestyramine and Mycophenolate mofetil can interact in a way that may be serious. Using them together is sometimes necessary, but it needs a deliberate decision by the prescriber, a plan for monitoring, and clear advice on the warning signs to watch for.
Cholestyramine belongs to Cardiovascular; Mycophenolate mofetil belongs to Miscellaneous.
چرا رخ می‌دهد
Bile acid sequestrant binding of mycophenolic acid and its glucuronide interrupts enterohepatic recirculation
اقدام لازم
Avoid combining; if cholestyramine is unavoidable give it well apart from mycophenolate and monitor graft function and mycophenolate exposure.
از داروساز چه بپرسید
- Does the benefit of taking both outweigh the risk in my case?
- Do I need any blood test, ECG or other check while on both?
- What early warning signs should I watch for, and what should I do if they appear?
ویژه اعضای Pro+
باز کردن کل صفحه
یک حساب بسازید و دوره آزمایشی Pro+ را شروع کنید تا توصیه‌های کامل مدیریت Cholestyramine و Mycophenolate mofetil، یادداشت‌های تکمیلی، جزئیات شواهد و بررسی‌کننده تداخل برای کل نسخه را باز کنید.
- Full clinical management advice
- Additional notes
- Evidence detail
- Interaction checker for a whole prescription
Pro+ را ۱۴ روز رایگان در وب امتحان کنید. بدون نیاز به کارت.
تداخلات دیگر Mycophenolate mofetil
- Adenovirus types 4 and 7 live + Mycophenolate mofetil منع مصرف
- Bcg vaccine live + Mycophenolate mofetil منع مصرف
- Influenza virus vaccine quadrivalent intranasal + Mycophenolate mofetil منع مصرف
- Measles mumps and rubella vaccine live + Mycophenolate mofetil منع مصرف
- Measles mumps rubella and varicella vaccine live + Mycophenolate mofetil منع مصرف
- Measles vaccine + Mycophenolate mofetil منع مصرف
تداخلات دیگر Cholestyramine
پرسش‌های متداول
Can I take Cholestyramine with Mycophenolate mofetil?
MediHelp rates the interaction as major. Cholestyramine and Mycophenolate mofetil can interact in a way that may be serious. Using them together is sometimes necessary, but it needs a deliberate decision by the prescriber, a plan for monitoring, and clear advice on the warning signs to watch for. Cholestyramine binds mycophenolic acid in the gut and interrupts its enterohepatic circulation, reducing exposure by about 40 percent. Loss of immunosuppression raises the risk of rejection.
How serious is the interaction between Cholestyramine and Mycophenolate mofetil?
MediHelp rates it major, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Avoid combining; if cholestyramine is unavoidable give it well apart from mycophenolate and monitor graft function and mycophenolate exposure.
What other medicines interact with Mycophenolate mofetil?
MediHelp also lists interactions of Mycophenolate mofetil with, for example, Adenovirus types 4 and 7 live, Bcg vaccine live, Influenza virus vaccine quadrivalent intranasal. The full list is on the Mycophenolate mofetil page.
تک‌نگاری کامل، دوزاژ و بررسی تداخل دارویی در برنامه MediHelp
مرجع کامل را باز کنید، تداخل چند دارو را بررسی کنید و از ابزارهای دوز در برنامه MediHelp استفاده کنید.
