تداخل‌های دارویی
Cyclosporine + Upadacitinib
شدت: منع مصرف
Cyclosporine and Upadacitinib: contraindicated interaction.
آخرین به‌روزرسانی
ویژه کادر درمان — فقط جهت مرجع. این صفحه خلاصه‌ای کوتاه است، توصیه پزشکی نیست و جایگزین بروشور رسمی یا قضاوت بالینی نمی‌شود. پیش از تجویز یا تحویل دارو همیشه بررسی کنید.
محتوای بالینی این صفحه فقط به زبان انگلیسی موجود است.
خلاصه
Cyclosporine is a potent immunosuppressant, and combined with upadacitinib it increases the risk of serious infection and malignancy. Upadacitinib labeling advises against use with potent immunosuppressants such as cyclosporine.
معنای این تداخل به زبان ساده
Cyclosporine and Upadacitinib are not normally used together. Taking them at the same time is expected to cause harm or make one of them unsafe, so a different medicine is usually chosen for one of the two.
چرا رخ می‌دهد
Additive immunosuppression through calcineurin and JAK inhibition.
اقدام لازم
Avoid the combination. Choose a regimen that does not pair a JAK inhibitor with cyclosporine.
از داروساز چه بپرسید
- Is there an alternative to one of these two medicines for me?
- If both are essential, who is monitoring me and how often?
- Which symptoms mean I should stop and seek help straight away?
ویژه اعضای Pro+
باز کردن کل صفحه
یک حساب بسازید و دوره آزمایشی Pro+ را شروع کنید تا توصیه‌های کامل مدیریت Cyclosporine و Upadacitinib، یادداشت‌های تکمیلی، جزئیات شواهد و بررسی‌کننده تداخل برای کل نسخه را باز کنید.
- Full clinical management advice
- Additional notes
- Evidence detail
- Interaction checker for a whole prescription
Pro+ را ۱۴ روز رایگان در وب امتحان کنید. بدون نیاز به کارت.
تداخلات دیگر Upadacitinib
پرسش‌های متداول
Can I take Cyclosporine with Upadacitinib?
MediHelp rates the interaction as contraindicated. Cyclosporine and Upadacitinib are not normally used together. Taking them at the same time is expected to cause harm or make one of them unsafe, so a different medicine is usually chosen for one of the two. Cyclosporine is a potent immunosuppressant, and combined with upadacitinib it increases the risk of serious infection and malignancy. Upadacitinib labeling advises against use with potent immunosuppressants such as cyclosporine.
How serious is the interaction between Cyclosporine and Upadacitinib?
MediHelp rates it contraindicated, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Avoid the combination. Choose a regimen that does not pair a JAK inhibitor with cyclosporine.
What other medicines interact with Upadacitinib?
MediHelp also lists interactions of Upadacitinib with, for example, Abrocitinib, Adenovirus types 4 and 7 live, Baricitinib. The full list is on the Upadacitinib page.
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