تداخل‌های دارویی
Dabigatran etexilate + Defibrotide
شدت: منع مصرف
Dabigatran etexilate and Defibrotide: contraindicated interaction.
آخرین به‌روزرسانی
ویژه کادر درمان — فقط جهت مرجع. این صفحه خلاصه‌ای کوتاه است، توصیه پزشکی نیست و جایگزین بروشور رسمی یا قضاوت بالینی نمی‌شود. پیش از تجویز یا تحویل دارو همیشه بررسی کنید.
محتوای بالینی این صفحه فقط به زبان انگلیسی موجود است.
خلاصه
Defibrotide has profibrinolytic activity and may enhance the bleeding risk of anticoagulants. Together with dabigatran this can cause serious hemorrhage.
معنای این تداخل به زبان ساده
Dabigatran etexilate and Defibrotide are not normally used together. Taking them at the same time is expected to cause harm or make one of them unsafe, so a different medicine is usually chosen for one of the two.
Dabigatran etexilate belongs to Cardiovascular; Defibrotide belongs to Cardiovascular.
چرا رخ می‌دهد
Additive pharmacodynamic effects on hemostasis from thrombin inhibition and enhanced fibrinolysis.
اقدام لازم
Avoid concurrent use; hold dabigatran during defibrotide therapy as directed by the specialist team, considering renal function for washout timing.
از داروساز چه بپرسید
- Is there an alternative to one of these two medicines for me?
- If both are essential, who is monitoring me and how often?
- Which symptoms mean I should stop and seek help straight away?
ویژه اعضای Pro+
باز کردن کل صفحه
یک حساب بسازید و دوره آزمایشی Pro+ را شروع کنید تا توصیه‌های کامل مدیریت Dabigatran etexilate و Defibrotide، یادداشت‌های تکمیلی، جزئیات شواهد و بررسی‌کننده تداخل برای کل نسخه را باز کنید.
- Full clinical management advice
- Additional notes
- Evidence detail
- Interaction checker for a whole prescription
Pro+ را ۱۴ روز رایگان در وب امتحان کنید. بدون نیاز به کارت.
تداخلات دیگر Dabigatran etexilate
تداخلات دیگر Defibrotide
- Alteplase + Defibrotide منع مصرف
- Apixaban + Defibrotide منع مصرف
- Argatroban + Defibrotide منع مصرف
- Dalteparin + Defibrotide منع مصرف
- Defibrotide + Edoxaban منع مصرف
- Defibrotide + Enoxaparin منع مصرف
پرسش‌های متداول
Can I take Dabigatran etexilate with Defibrotide?
MediHelp rates the interaction as contraindicated. Dabigatran etexilate and Defibrotide are not normally used together. Taking them at the same time is expected to cause harm or make one of them unsafe, so a different medicine is usually chosen for one of the two. Defibrotide has profibrinolytic activity and may enhance the bleeding risk of anticoagulants. Together with dabigatran this can cause serious hemorrhage.
How serious is the interaction between Dabigatran etexilate and Defibrotide?
MediHelp rates it contraindicated, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Avoid concurrent use; hold dabigatran during defibrotide therapy as directed by the specialist team, considering renal function for washout timing.
What other medicines interact with Dabigatran etexilate?
MediHelp also lists interactions of Dabigatran etexilate with, for example, Ketorolac, Mifepristone, Abciximab. The full list is on the Dabigatran etexilate page.
تک‌نگاری کامل، دوزاژ و بررسی تداخل دارویی در برنامه MediHelp
مرجع کامل را باز کنید، تداخل چند دارو را بررسی کنید و از ابزارهای دوز در برنامه MediHelp استفاده کنید.
