تداخل‌های دارویی
Dantrolene + Dextromoramide
شدت: شدید
Dantrolene and Dextromoramide: major interaction.
آخرین به‌روزرسانی
ویژه کادر درمان — فقط جهت مرجع. این صفحه خلاصه‌ای کوتاه است، توصیه پزشکی نیست و جایگزین بروشور رسمی یا قضاوت بالینی نمی‌شود. پیش از تجویز یا تحویل دارو همیشه بررسی کنید.
محتوای بالینی این صفحه فقط به زبان انگلیسی موجود است.
خلاصه
Dextromoramide is a potent opioid analgesic that causes sedation and respiratory depression, and dantrolene adds drowsiness and muscle weakness. Together they may increase the risk of excessive sedation and impaired breathing, particularly in frail patients or at higher doses.
معنای این تداخل به زبان ساده
Dantrolene and Dextromoramide can interact in a way that may be serious. Using them together is sometimes necessary, but it needs a deliberate decision by the prescriber, a plan for monitoring, and clear advice on the warning signs to watch for.
چرا رخ می‌دهد
Additive CNS depression from opioid action combined with dantrolene sedation and muscle weakness.
اقدام لازم
Start with the lowest effective opioid dose and titrate slowly while monitoring sedation and respiratory rate. Counsel patients to avoid driving and other CNS depressants.
از داروساز چه بپرسید
- Does the benefit of taking both outweigh the risk in my case?
- Do I need any blood test, ECG or other check while on both?
- What early warning signs should I watch for, and what should I do if they appear?
ویژه اعضای Pro+
باز کردن کل صفحه
یک حساب بسازید و دوره آزمایشی Pro+ را شروع کنید تا توصیه‌های کامل مدیریت Dantrolene و Dextromoramide، یادداشت‌های تکمیلی، جزئیات شواهد و بررسی‌کننده تداخل برای کل نسخه را باز کنید.
- Full clinical management advice
- Additional notes
- Evidence detail
- Interaction checker for a whole prescription
Pro+ را ۷ روز رایگان در وب امتحان کنید. بدون نیاز به کارت.
تداخلات دیگر Dantrolene
پرسش‌های متداول
Can I take Dantrolene with Dextromoramide?
MediHelp rates the interaction as major. Dantrolene and Dextromoramide can interact in a way that may be serious. Using them together is sometimes necessary, but it needs a deliberate decision by the prescriber, a plan for monitoring, and clear advice on the warning signs to watch for. Dextromoramide is a potent opioid analgesic that causes sedation and respiratory depression, and dantrolene adds drowsiness and muscle weakness. Together they may increase the risk of excessive sedation and impaired breathing, particularly in frail patients or at higher doses.
How serious is the interaction between Dantrolene and Dextromoramide?
MediHelp rates it major, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Start with the lowest effective opioid dose and titrate slowly while monitoring sedation and respiratory rate. Counsel patients to avoid driving and other CNS depressants.
What other medicines interact with Dantrolene?
MediHelp also lists interactions of Dantrolene with, for example, Benzhydrocodone / acetaminophen, Buprenorphine long-acting, Buprenorphine subdermal implant. The full list is on the Dantrolene page.
تک‌نگاری کامل، دوزاژ و بررسی تداخل دارویی در برنامه MediHelp
مرجع کامل را باز کنید، تداخل چند دارو را بررسی کنید و از ابزارهای دوز در برنامه MediHelp استفاده کنید.
