تداخل‌های دارویی
Dinoprostone + Oxytocin
شدت: شدید
Dinoprostone and Oxytocin: major interaction.
آخرین به‌روزرسانی
ویژه کادر درمان — فقط جهت مرجع. این صفحه خلاصه‌ای کوتاه است، توصیه پزشکی نیست و جایگزین بروشور رسمی یا قضاوت بالینی نمی‌شود. پیش از تجویز یا تحویل دارو همیشه بررسی کنید.
محتوای بالینی این صفحه فقط به زبان انگلیسی موجود است.
خلاصه
Dinoprostone and oxytocin both stimulate uterine contractions, and giving them close together can produce excessive uterine activity. This may lead to uterine tachysystole, fetal heart rate abnormalities, or uterine rupture, particularly in women with a previous uterine scar or high parity.
معنای این تداخل به زبان ساده
Dinoprostone and Oxytocin can interact in a way that may be serious. Using them together is sometimes necessary, but it needs a deliberate decision by the prescriber, a plan for monitoring, and clear advice on the warning signs to watch for.
Dinoprostone belongs to Endocrine; Oxytocin belongs to Endocrine.
چرا رخ می‌دهد
Additive pharmacodynamic uterotonic effects, with prostaglandin-induced sensitization of the myometrium to oxytocin.
اقدام لازم
Allow an interval after removing dinoprostone (commonly at least 30 minutes for the vaginal insert, longer for gel per labeling) before starting oxytocin. Monitor uterine activity and fetal heart rate continuously.
از داروساز چه بپرسید
- Does the benefit of taking both outweigh the risk in my case?
- Do I need any blood test, ECG or other check while on both?
- What early warning signs should I watch for, and what should I do if they appear?
ویژه اعضای Pro+
باز کردن کل صفحه
یک حساب بسازید و دوره آزمایشی Pro+ را شروع کنید تا توصیه‌های کامل مدیریت Dinoprostone و Oxytocin، یادداشت‌های تکمیلی، جزئیات شواهد و بررسی‌کننده تداخل برای کل نسخه را باز کنید.
- Full clinical management advice
- Additional notes
- Evidence detail
- Interaction checker for a whole prescription
Pro+ را ۱۴ روز رایگان در وب امتحان کنید. بدون نیاز به کارت.
تداخلات دیگر Oxytocin
پرسش‌های متداول
Can I take Dinoprostone with Oxytocin?
MediHelp rates the interaction as major. Dinoprostone and Oxytocin can interact in a way that may be serious. Using them together is sometimes necessary, but it needs a deliberate decision by the prescriber, a plan for monitoring, and clear advice on the warning signs to watch for. Dinoprostone and oxytocin both stimulate uterine contractions, and giving them close together can produce excessive uterine activity. This may lead to uterine tachysystole, fetal heart rate abnormalities, or uterine rupture, particularly in women with a previous uterine scar or high parity.
How serious is the interaction between Dinoprostone and Oxytocin?
MediHelp rates it major, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Allow an interval after removing dinoprostone (commonly at least 30 minutes for the vaginal insert, longer for gel per labeling) before starting oxytocin. Monitor uterine activity and fetal heart rate continuously.
What other medicines interact with Oxytocin?
MediHelp also lists interactions of Oxytocin with, for example, Carboprost tromethamine, Ephedrine, Fexinidazole. The full list is on the Oxytocin page.
تک‌نگاری کامل، دوزاژ و بررسی تداخل دارویی در برنامه MediHelp
مرجع کامل را باز کنید، تداخل چند دارو را بررسی کنید و از ابزارهای دوز در برنامه MediHelp استفاده کنید.
