تداخلهای دارویی
Dobutamine + Methylergonovine
شدت: شدید
Dobutamine and Methylergonovine: major interaction.
آخرین بهروزرسانی
ویژه کادر درمان — فقط جهت مرجع. این صفحه خلاصهای کوتاه است، توصیه پزشکی نیست و جایگزین بروشور رسمی یا قضاوت بالینی نمیشود. پیش از تجویز یا تحویل دارو همیشه بررسی کنید.
محتوای بالینی این صفحه فقط به زبان انگلیسی موجود است.
خلاصه
Methylergonovine is a potent uterine and vascular constrictor that can raise blood pressure and cause vasospasm. Dobutamine adds adrenergic cardiovascular stimulation, so hypertension and ischemia are more likely. Severe hypertension has been reported with ergot alkaloids and sympathomimetics.
معنای این تداخل به زبان ساده
Dobutamine and Methylergonovine can interact in a way that may be serious. Using them together is sometimes necessary, but it needs a deliberate decision by the prescriber, a plan for monitoring, and clear advice on the warning signs to watch for.
چرا رخ میدهد
Additive vasoconstriction and cardiovascular stimulation.
اقدام لازم
Avoid the combination where alternatives exist, for example other uterotonics in postpartum hemorrhage. If both are required, monitor blood pressure continuously and treat hypertension promptly.
از داروساز چه بپرسید
- Does the benefit of taking both outweigh the risk in my case?
- Do I need any blood test, ECG or other check while on both?
- What early warning signs should I watch for, and what should I do if they appear?
ویژه اعضای Pro+
باز کردن کل صفحه
یک حساب بسازید و دوره آزمایشی Pro+ را شروع کنید تا توصیههای کامل مدیریت Dobutamine و Methylergonovine، یادداشتهای تکمیلی، جزئیات شواهد و بررسیکننده تداخل برای کل نسخه را باز کنید.
- Full clinical management advice
- Additional notes
- Evidence detail
- Interaction checker for a whole prescription
Pro+ را ۱۴ روز رایگان در وب امتحان کنید. بدون نیاز به کارت.
تداخلات دیگر Dobutamine
پرسشهای متداول
Can I take Dobutamine with Methylergonovine?
MediHelp rates the interaction as major. Dobutamine and Methylergonovine can interact in a way that may be serious. Using them together is sometimes necessary, but it needs a deliberate decision by the prescriber, a plan for monitoring, and clear advice on the warning signs to watch for. Methylergonovine is a potent uterine and vascular constrictor that can raise blood pressure and cause vasospasm. Dobutamine adds adrenergic cardiovascular stimulation, so hypertension and ischemia are more likely. Severe hypertension has been reported with ergot alkaloids and sympathomimetics.
How serious is the interaction between Dobutamine and Methylergonovine?
MediHelp rates it major, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Avoid the combination where alternatives exist, for example other uterotonics in postpartum hemorrhage. If both are required, monitor blood pressure continuously and treat hypertension promptly.
What other medicines interact with Dobutamine?
MediHelp also lists interactions of Dobutamine with, for example, Budesonide-formoterol, Dihydroergotamine intranasal, Dihydroergotamine. The full list is on the Dobutamine page.
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