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Dobutamine + Methylergonovine

شدت: شدید

Dobutamine and Methylergonovine: major interaction.

آخرین به‌روزرسانی

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محتوای بالینی این صفحه فقط به زبان انگلیسی موجود است.

خلاصه

Methylergonovine is a potent uterine and vascular constrictor that can raise blood pressure and cause vasospasm. Dobutamine adds adrenergic cardiovascular stimulation, so hypertension and ischemia are more likely. Severe hypertension has been reported with ergot alkaloids and sympathomimetics.

معنای این تداخل به زبان ساده

Dobutamine and Methylergonovine can interact in a way that may be serious. Using them together is sometimes necessary, but it needs a deliberate decision by the prescriber, a plan for monitoring, and clear advice on the warning signs to watch for.

سطح شواهد: Moderate

چرا رخ می‌دهد

Additive vasoconstriction and cardiovascular stimulation.

اقدام لازم

Avoid the combination where alternatives exist, for example other uterotonics in postpartum hemorrhage. If both are required, monitor blood pressure continuously and treat hypertension promptly.

از داروساز چه بپرسید

  • Does the benefit of taking both outweigh the risk in my case?
  • Do I need any blood test, ECG or other check while on both?
  • What early warning signs should I watch for, and what should I do if they appear?

Bring a full list of your medicines, including over-the-counter products, supplements and herbal remedies, to every pharmacy visit.

ویژه اعضای Pro+

باز کردن کل صفحه

یک حساب بسازید و دوره آزمایشی Pro+ را شروع کنید تا توصیه‌های کامل مدیریت Dobutamine و Methylergonovine، یادداشت‌های تکمیلی، جزئیات شواهد و بررسی‌کننده تداخل برای کل نسخه را باز کنید.

  • Full clinical management advice
  • Additional notes
  • Evidence detail
  • Interaction checker for a whole prescription

Pro+ را ۱۴ روز رایگان در وب امتحان کنید. بدون نیاز به کارت.

پرسش‌های متداول

Can I take Dobutamine with Methylergonovine?

MediHelp rates the interaction as major. Dobutamine and Methylergonovine can interact in a way that may be serious. Using them together is sometimes necessary, but it needs a deliberate decision by the prescriber, a plan for monitoring, and clear advice on the warning signs to watch for. Methylergonovine is a potent uterine and vascular constrictor that can raise blood pressure and cause vasospasm. Dobutamine adds adrenergic cardiovascular stimulation, so hypertension and ischemia are more likely. Severe hypertension has been reported with ergot alkaloids and sympathomimetics.

How serious is the interaction between Dobutamine and Methylergonovine?

MediHelp rates it major, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Avoid the combination where alternatives exist, for example other uterotonics in postpartum hemorrhage. If both are required, monitor blood pressure continuously and treat hypertension promptly.

What other medicines interact with Dobutamine?

MediHelp also lists interactions of Dobutamine with, for example, Budesonide-formoterol, Dihydroergotamine intranasal, Dihydroergotamine. The full list is on the Dobutamine page.

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